Acute tubular necrosis Flashcards

1
Q

What is the most common cause of AKI?

A

Acute tubular necrosis

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2
Q

What is the pathophysiology of ATN?

A

Necrosis of renal tubular epithelial cells severely effects the functioning of kidneys

  • in the very early stages of ATN is reversible if the cause is removed.
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3
Q

What are the two main causes of ATN?

A
  1. Ischaemia - shock / sepsis
  2. Nephrotoxins -
    - aminoglycosides
    - myoglobulin secondary to rhabdomyolysis
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4
Q

U and E results of ATN?

A
  1. Raised creatinine
  2. Raised potassium
  3. Raised urea
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