Acute Leukemia Cases--Nikcevich Flashcards
1
Q
11q23 transformation in AML indicates what
A
poor prognosis
2
Q
11q23 transformation in AML is often caused by…
A
previous chemo
usually alkylating agents
3
Q
Prognostic feature: Auer rods
A
positive
(better outcome)
4
Q
t(8;21), t(16;16), t(15;17)
A
good prognostic features
5
Q
What do monocytes have that makes them easy to see on a smear?
A
nuclear clefts
6
Q
What type of cell is diagnostic for acute promyelocytic leukemia?
A
Faggot cell
7
Q
What is donor chimerism?
A
all peripheral blood is from donor tissue
8
Q
A super duper high WBC with lots of blasts might cause this set of complications
A
hyperviscocity
heart –> ischemia
retina –> blurred vision