Acute inflammation 2

Question 1

What are the immediate systemic effects of acute inflammation?

Answer 1

Pyrexia
General feeling of being unwell/malaise
Neutrophilia- increased white blood cell count

Question 2

What are the longer term effects of acute inflammation?

Answer 2

Lymphadenopathy
Weightloss
Anaemia

Question 3

What are the potential complications of acute inflammation?

Answer 3

Septic shock(part of a severe type of sepsis) /sepsis
bacteraemia
septicaemia
Toxaemia

Question 4

Give 3 examples of acute inflammation mediators that are released from cells in the inflamed area and what they do

Answer 4

Histamine- causes vasodilation and increases permeability
Serotonin- causes vasoconstriction to prevent leakage from a damaged vessel
Nitric oxide- relaxes smooth muscles

Question 5

Given an example of an endothelial cell mediator used in inflammation

Answer 5

ICAM-1 helps neutrophils to adhere to endothelium