Acute and Chronic Inflammation Flashcards
The most common mechanism facilitating increased vascular permeability
a) Endothelial injury
b) leukocyte – mediated endothelial injury
c) Gaps due to endothelial contraction
d) increased transcytosis
C
Sources of histamine and serotonin is/are
a) vast cells
b) Basophils
c) platelet
d) AOTA
D
Which of the following generates prostaglandin and thromboxanes
a) lipoxygenase
b) cycloxgenase
c) kinins
d) complement
C
Which is/are true about acute information?
a) In chemotaxis, the injurious agent goes to the phagocytic cell for phagocytes
b) In activation of phagocytic all, secretions are not only confined to phagosome but also leaks out to the extracellular matrix
c) Leukocyte adhesion consists of migration, rolling, and adhesion
d) B and C are true
D
Protein C, fibronectin and amyloid proteins are examples of
a) chemokines
b) acute phase pro
c) cytokines
d) complement
B
Leukoid reaction occurs when:
a) leukocyte count reaches 15,000-20,000 cells/mL
b) leukocyte count reaches 40,000 – 100,000 cells/mL
c) leukocyte count drops 5,000 – 10,000 cells/mL
d) leukocyte count drops 1,000 – 5,000 cell/mL
B
Which statement is correct?
a) In acute inflammation, the major players are mononuclear inflammatory cells
b) The most common cause of leukocyte defect is bone marrow suppression
c) The chemical mediators of inflammation does not have the potential to have harmful effects
d) Kinin, clotting, fibrinolytic, and complement cascades are interellated systems that are activated by factor V
B
Effects of tumor necrosis factor
a) increase fibroblast proliferation
b) decrease acute phase proteins
c) increase anticoagulant activity
d) decrease cytokine secretion
A
True of Nitric Oxide
a) pleiomorphic of vasodilation
b) aka endothelium-derived relaxation factor
c) inhibits platelet aggregation and adhesion
d) all of the above
B
Outcome/s of acute inflammation
a) resolution
b) abscess formation
c) chronic inflammation
d) all of the above
D
Which of the following organs is normally involved in low-level proliferation but is capable of rapid replication upon stimulation?
a) Skeletal muscle
b) liver
c) bone marrow
d) neurons
B
A cell producing substances that affect target cells in close proximity:
a) Paracrine
b) Endocrine
c) Paracrine
d) Ecrine
B
Which statement is correct?
a. Acute inflammation is typified by infiltration of mononuclear lymphocytes
b. Chronic inflammation can occur without prior acute inflammation
c. Abscess formation is part of fibrinous inflammation
d. Suppurous inflammation produces transudates
B
Which of the following is inhibited by steroids
a. Phospholipase
b. Prostaglandin
c. Prostacyclin
d. Thromboxane
B
A type of chronic inflammation characterized by activated macrophage with a modified epithelial like (epitheloid) appearance.
a. Granulomatous inflammation
b. Suppurative inflammation
c. Serous inflammation
d. purulent inflammation
A
This condition happens when the embolus has gained access into the arterial circulation.
a. Systematic embolism
b. Pulmonary embolism
c. Amniotic Fluid embolism
d. Air embolism
A
What is/are the source/s of histamine and serotonin?
a. Mast cell
b. Basophils
c. Platelets
d. AOTA
D