Activated Charcoal Flashcards
Generic Name:
Activated Charcoal
Trade Name:
ActiDose
Class:
Absorbent
Supplied:
25g/120mL bottle
Mechanism of Action: Pharmacological:
Physical binding (absorption) of toxins from GI tract.
Mechanism of Action: Clinical:
Prevents/reduces systemic absorption of toxins
Indications and Field Use:
- Sole prehospital therapy of oral ingestion of toxic substances
- Pre-lavage of oral ingestions of toxic substances
Contraindications:
- Ingestion of caustics
- Ingestion of hydrocarbons (relative)
- Oral administration to comatose patient
- Simultaneous administration of other oral drugs
Adverse Reactions:
- May provoke vomiting
- May worsen poison induced illness
Incompatibilities/Drug Interactions:
- Ineffective for iron, lithium, heavy metals, and other ions.
- May reduce the effectiveness of other treatments (Mucomyst) in pure acetaminophen OD’s.
- Since charcoal bonds with whatever it is mixed with, flavoring with drinks reduces effectiveness.
Adult Dosage:
30-60g (1-2g/kg); if not in pre-mixed slurry, mix one part charcoal with four parts water.
Pediatric Dosage:
0.5 - 1.0 g/kg; if not in pre-mixed slurry, mix one part charcoal with four parts water.
Routes of Administration:
Oral (po), Nasogastric tube (ng), Orogastric (og)
Onset of Action:
Immediate
Peak Effects:
Not applicable