Action Potential Flashcards
Stages of action potential
- depolarisation
- repolarisation
- hyperpolarisation
- return to resting potential
Depolarisation
- Stimulus causes gated Na+ channels to open causing permeability of Na+ to increase
-Na+ diffuse down electrochemical gradient into axon, making inside of the neurone less negative - if stimulus is great enough and threshold value is reached, action potential occur
- more Na+ channels open, membrane becomes depolarised
Repolarisation
- K+ channels open/Na+ channels close
- permeability to k+ increase
- k+ diffuse out of neurone down electrochemical gradient
- neurone becomes more negative compared to outside
Hyperpolaristaion
- K+ channels slow to close
- neurone more negative than the outside
What is the refractory period
The Period where another action potential cannot take place
Why is refractory period important
- So action potential don’t overlap
- ensures unidirectional impulse
-limits frequency of impulse transmission - produces discrete impulses
All or nothing principle
Any stimulus that causes the membrane to reach threshold potential will generate an action potential
3 factor that affect speed of conductance
- myelin sheath
- axon diameter
- temperature
How does axon diameter affect speed of conductance
Greater diameter = faster
- less resistance to flow of ions
- less leakage of ions, easier t maintain membrane potential
How does temp affect seed of conductance
Higher temp = faster
- faster rate of diffusion
- faster rate of respiration = more ATP for active transport to re-establish resting potential
Temp to high = denature
Stats test used to determine wether a factor has a significant effect on the speed of conductance
T test - Comparing means of continuous data