ACS Flashcards

1
Q

ACS includes?

A

unstable angina
NSTEMI
STEMI

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2
Q

incidence of STEMI

A

5/1000

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3
Q

Pathophysiology

A
  • plaque rupture, thrombosis & inflammation

- rarely coronary spasm

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4
Q

modifiable risk factors of ACS

A
  • HTN
  • DM
  • Smoking
  • ↑cholesterol
  • Obesity
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5
Q

non-modifiable risk factors of ACS

A
  • age
  • male
  • FH (MI <55 years)
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6
Q

symptoms of ACS

A
  • Radiates to left jaw or arm
  • Nausea
  • Sweating
  • Dyspnoea
  • Palpitations
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7
Q

Other symptoms for diabetic patients who may present without chest pain

A
  • Syncope
  • Delirium
  • Post-op oliguria / hypotension
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8
Q

signs of ACS

A
  • Anxiety
  • Pallor Sweating
  • Pulse ↑/↓
  • BP ↑/↓
  • 4th heart sound
  • Signs of LVF (basal creps, ↑ JVP, 3rd HS)
  • Pansystolic Murmur: papillary muscle dysfunction / rupture
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9
Q

differential diagnosis of ACS

A
  • Angina
  • Peri / endo / myocarditis
  • Dissection
  • PE, pneumothorax, pneumonia
  • Costochondritis
  • GI: e.g. GORD, spasm
  • Anxiety
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10
Q

ECG changes for STEMI

A
  • Normal
  • ST elevation + hyperacute (tall) T waves
  • Q waves: full-thickness infarct
  • Normalisation of ST segments
  • T wave inversion
  • (New onset LBBB also = STEMI)
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11
Q

ECG changes for NSTEMI

A
  • ST depression

- T wave inversion

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12
Q

no Q waves on ECG indicates?

A

subendocardial infarct

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13
Q

bloods for ACS

A
  1. Troponin T/I
    - Myofibrillar proteins linking actin and myosin
    - Elevated from 3-12h
    - need 12h trop to exclude MI
    - Peak 24h
    - Baseline from 5-14d
  2. FBC, U+E, glucose, lipids, clotting
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14
Q

CXR for suspected ACS

A
  • Cardiomegaly
  • Pulmonary oedema
  • Widened mediastinum: aortic rupture
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15
Q

diagnose unstable angina when?

A
  • typical symptoms
  • no ST elevation
  • negative troponin
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16
Q

treatment for STEMI

A

PCI or thrombolysis

17
Q

treatment for NSTEMI/unstable angina

A

medical + elective angio ± PCI/CABG

18
Q

prognosis of STEMI patients?

A

30 day mortality ~15%

19
Q

prognosis for NSTEMI

A

overall mortality 1-2%