Acromegaly Flashcards
1
Q
what is acromegaly
A
where the anterior pituitary gland releases too much GH
2
Q
how does acromegaly present in adults
A
insidious onset;
hyperhydriasis, headaches, joint pain, macroglossia, coarsening of features, enlarged nose, prognathism, deepened voice, obstructive sleep apnoea, enlargement of hands and feet
3
Q
how does acromegaly present in children
A
gigantism
4
Q
how to investigate acromegaly
A
OGTT
MRI brain
5
Q
management of acromegaly
A
complete resection
somatostatin analogues such as octreotide and lanreotide
radiotherapy
6
Q
what does acromegaly increase the risk of
A
hypertension,
impaired glucose tolerance/ insulin resistance,
osteoporosis
colonic polyps/ cancer
IHD (ischaemic heart disease)
cerebrovascular diseases (hypertension also increases the risk of this)
