Acquired Immune Response

Question 1

Helps regulate T-lymphocytes.

Answer 1

Major histocompatibility complex (MHC) products

Question 2

Old name of MHC

Answer 2

Human leukocyte antigen (HLA)

Question 3

The specific immune response to parasites begins processed by

Answer 3

CD4 T-helper Lymphocytes.

Question 4

What is the subsets of CD4 T-Lymphocyte?

Answer 4

Th1 and Th2

Question 5

Th1 lymphocytes produce

Answer 5

Gamma interferon
Interleukin-2
Macrophage

Question 6

What subset of t-helper cell mediates cell-mediated immune response?

Answer 6

Th1 lymphocyte

Question 7

Th1 acitivates____ through gamma interferon and interleukin-2

Answer 7

Cytotoxic lymphocytes

Question 8

T or F
Parasitic-specific antigen induces clonal expansion of parasite-specific T-Lymphocyte .

Answer 8

True

Question 9

Cell mediated immunity may act by

Answer 9

• Direct cytotoxicity
• Indirectly on natural killer cells

Question 10

Migrating larvae of ____ are killed through cell-mediated activity.

Answer 10

Toxocara canis

Question 11

What is the product of Th2?

Answer 11

Interleukins 4,5,6

Question 12

It enhances the proliferation and differentiation of B lymphocyte into plasma cells.

Answer 12

4,5,6 interleukins

Question 13

Responsible for immunoglobulin production.

Answer 13

B-lymphocyte

Question 14

In Helminths infections, the mkst common responses includes____.

Answer 14

Eosinophilia and elevated serum IgE.

Question 15

Lumen dwelling helminths.

Answer 15

Ascaris lumbricoides
Trichuris trichiura

Question 16

Lymphatic dwelling helminths

Answer 16

Wuchereria bancrofti
Brugia malayi

Question 17

This antibody is bound in mast cells, Eosinophil, and gobket cells. They can mediate the eventual expulsion of adult gastrointestinal helminths.

Answer 17

IgE

Question 18

This immunoglobulin invloves in inflammatory, cytotoxic action

Answer 18

IgE

Question 19

What is the indication of increasing eosinophil?

Answer 19

Hypersensitivity/ allergic reaction
Parasitic infection

Question 20

It is an antibody dependent cell-mediated cytotoxicity (ADCC)

Answer 20

IgE

Question 21

There are a variety of activating molecules expressed by the eosinophil that mediates (ADCC)
What are they?

Answer 21

Eosinophil activating factor (EAF)
Interleukin-5
Granulocyte monocyte colony stimulating factor (GM-CSF)

Question 22

Destruction of microfilariae has been attributed to ADCC mediated by___.

Answer 22

IgE and eosinophil

Question 23

Aside from IgE and eosinophil, what else are involved in ADCC?

Answer 23

Neutrophils and platelets

Question 24

They can act on mast cells and basophils, which lead to degranulation and eventual release of pharmacologically active substances.

Answer 24

Homocytotrophic IgG1 and IgE

Question 25

Unregulated activation can results in ___.

Answer 25

Anaphylactic Type 1 hypersensitive

Question 26

Rupture of echinococcus granulosus hydatid cyst.

Answer 26

Type 1 hypersensitivity

Question 27

The combine activity of ____ can prevent penetration of erythrocytes by Plasmodium spp. And Babesia spp.

Answer 27

IgG and IgM

Question 28

Combine activity of IgG and IgM can is effective against gastrointestinal helminths.

Answer 28

False - ineffective

Question 29

The complement activity of these immunoglobulin can mediate lysis of trypomastigotes of Trypanosoma cruzi.

Answer 29

IgG and IgM

Question 30

The secretion of this immunoglobulin in the intestine protect agaisnts metacestode and GI infections.

Answer 30

IgA

Question 31

IgM and IgA mediate…

Answer 31

ADCC in Giardia lamblia infection

Question 32

Cryptosporidium infection is self limited due to the combined action of ___.

Answer 32

IgA ans IgG with cell mediated immunity

Question 33

T or F
The host can activate its non-specific, specific, humoral, and cell-mediated defenses all at the same time.

Answer 33

True