Acne

Question 1

Acne Vulgaris is disorder of __ unit

Answer 1

Pilosebaceous

Question 2

There is 1 and 2 of keratinocytes leading to plugging of 3; There is also excess 4 due to 5 stimulation; The bacteria involved is 6, a gram 7. There is also 8

Answer 2

1. hyperproliferation
2. abnormal differentiation
3. follicular infundibulum
4. sebum production
5. androgen
6. propionibacterium acnes
7. Gram + rod (breaks down sebum and inflammatory mediators)
8. inflammation

Question 3

Open comedones are 1 and closed comedones are 2

Answer 3

1. white heads

2. black heads

Question 4

Acne Vulgaris can be 1, 2, 3

Answer 4

1. comedonal: open/closed
2. inflammatory: papules/pustules
3. nodulocystic: nodules/cysts

Question 5

Acne ___ has systemic manifestations including fever, arthragias, __, and __

Answer 5

1. Fulminas
2. osteolytic bone lesions
3. hepatosplenomegaly

Question 6

Comedonal acne can be treated with ___

Answer 6

topical retinoids, benzoyl peroxide, azelaic/salicylic acids (mild to moderate)

Question 7

Benzoyl peroxide is more effective when combined with ___ than either used alone (dec___)

Answer 7

antibiotic; dec antibiotic resistance

Question 8

Moderate to sever inflammatory acne w/without comedone lesions can be treated with __

Answer 8

topical benzoyl peroxide and oral antibiotics (rather than just topical agents alone)

Question 9

Severe Acne Vulgaris is treated with ___ derivative

Answer 9

Vit A (retinoid, Isotretinoin, highly teratogenic)

Question 10

Hormonal agents used in moderate to severe acne vulgaris are __

Answer 10

oral contraceptives and sipronolactone

Question 11

Risk factors for Rosacea?

Answer 11

1. fair skinned, actinic damage, genetic, flushing propensity

Question 12

4 clinical subtypes of Rosacea? Which types are primarily localized on central face?

Answer 12

1. Erythematotelangiectatic
2. Papulopustular
3. Phymatous
4. Ocular rosacea

Erythematotelangictatis and papulopustular

Question 13

Phymatous rosacea exhibit 1 mostly involving 2

Answer 13

1. tissue hypertrophy, irregular contours and thickened skin

2. nose (rhinophyma), chin, forehead, cheeks

Question 14

Ocular rosacea clinicall manifest itself as 1 and 2

Answer 14

1. conjunctival hyperemia
2. anterior blepharitis, keratitis, lid margin telangiectases, abnormal tearing, cicatricial conjunctivits, hordeolum

dry eye, stinging, burning, pruitus, photosensitivity, blurry vision

Question 15

Treatment of erythematotelangictatic rosacea is ___

Answer 15

1. educated on avoidance of triggers, sun protection, gentle skin care

Question 16

Inflammatory/paupulopustular subtype of rosacea can be aided by __ in mild cases, and __ in severe cases, and __ in refractory papulopusturlar rosacea

Answer 16

metronidazole/azelaic acid;
oral tetracycline
oral isotretinoin