Acing the G.I. boards 2 Flashcards

1
Q

Hyperkeratosis on palms and soles plus dysphasia?

Associated with?

A

Tylosis (Howell-Evans syndrome)

Leukoplakia, squamous cell esophageal cancer

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2
Q

Constipation + failure to relax internal anal sphincter with balloon dilation?

A

Hirschsprung’s disease

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3
Q

Pathognomonic for intervascular hemolysis?

A

Urine hemosiderin

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4
Q

Thick gastric folds + diarrhea + low albumin + edema

A

Ménétrier’s

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5
Q

Arterial dissection + cirrhosis + liver biopsy with PAS-positive globules

A

Alpha one antitrypsin deficiency

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6
Q

Difference in gastrin level, gastric pH, and parietal cell mass in corpus versus antral H. pylori?

A

High gastrin, high gastric pH, decreased parietal cell mass (parietal cells impaired)

High gastrin, low gastric pH, increased parietal cell mass (somatostatin secreting D cells impaired)

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7
Q

Luminal nodule + myeloperoxidase positivity + high LDH?

Most of these patients will develop?

A

Granulocytic sarcoma (chloroma) - green in color

Leukemia

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8
Q

Young patient + jaundice + abdominal pain + RUQ palpable mass?

A

Choledochal cyst III

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9
Q

Pre-menopausal woman with cyclic abdominal pain +/- subepithelial GI lesions

A

G.I. endometriosis

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10
Q

Hepatitis C + low complement + pupuric rash + renal disease + paresthesias

A

Mixed cryoglobulinemia

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11
Q

Young adult + abdominal pain + low complement + purpuric rash

A

Henoch-Schönlein Purpura

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12
Q

Hematomas + cobblestone tongue + bumps on face?

A

Cowden syndrome

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13
Q

AIDS + jaundice + cystic blood-filled space on liver biopsy?

Treatment?

A

peliosis hepatitis (Bartonella)

Erythromycin

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14
Q

Diarrhea after consuming chocolate milk

A

Listeria

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15
Q

Diarrhea + tropics + high MCV anemia? Treatment?

A

Tropical sprue

Tetracycline + folate for 6-12 months

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16
Q

Infectious diseases that consist of PAS positive foamy macrophages? Distinguished by this stain?

A

Whipples disease and MAC

AFP stain (positive in MAC)

17
Q

Low serum protein + diarrhea + focal white spots in small bowel?

A

Intestinal lymphangiectasia

18
Q

TCAs - Most sedating/constipating to least?

A

Amitriptyline >nortriptyline> desipramine

19
Q

Peripheral mu opiate receptor antagonist used for postoperative ileus?

A

alvimopan (Entereg)

20
Q

HIV + tenesmus + bloody diarrhea and saddle paresthesias?

If ulcer, biopsy where?

A

HSV proctitis

Edge

21
Q

HIV + bloody diarrhea + colonic ulcers with “owls eye” inclusion body

Biopsy ulcer where?

A

CMV colitis

Center

22
Q

HIV + diarrhea plus eosinophilia + travel to Africa/Haiti

Crystals in stool?

A

isospora

eosinophil granules that contain large amounts of Charcot-Leyden protein

23
Q

Mediterranean origin + abdominal pain + elevated ESR?

Gene? Treatment? Long-term risk of?

A

Familial Mediterranean fever

Pyrin; colchicine; amyloidosis 

24
Q

 CD117 positive + 4th layer subepithelial mass

A

GIST

25
Q

Actin positive + CD117 negative + fourth layer subepithelial mass?

A

Leiomyoma

26
Q

Spherical + anechoic + subepithelial gastric mass?

A

Duplication cyst

27
Q

Gastric mass + 2nd/3rd layer + enterochromaffin cells

A

Carcinoid

28
Q

Gastric mass + 4th layer + Vimentin positive

A

Glomus tumor

29
Q

Gastric mass +4th layer + S-100 positive?

A

Schwannoma

30
Q

Cavernous hemangioma + G.I. bleeding + history of intussusception

Treatment?

A

Blue rubber bleb nevus syndrome

Oral iron. Usually too many lesions for surgery

31
Q

Cutaneous hemangioma/Varicose veins + G.I. hemangioma + bone overgrowth + soft tissue hyperplasia

A

Klippel-Trenaunay-Weber Syndrome (vascular malformation syndrome)

32
Q

Villous blunting with Howell-Jolly bodies

A

Celiac