Acid-Base Physiology DSA Flashcards

1
Q

What is an acid?

A

proton donor

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2
Q

What is a base?

A

proton acceptor

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3
Q

What is a strong acid?

A

completely or almost completely dissociated into a hydrogen ion and its conjugate base in dilute aqueous solution

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4
Q

What is hydrogen ion activity in pure water?

A

10^-7

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5
Q

arterial oxygen PaO2

A

80-100 mm Hg (age dependent)

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6
Q

arterial carbon dioxide PaCO2

A

35-45 mm Hg (use 40 mm Hg)

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7
Q

arterial pH (pHa)

A

7.35-7.45 (use 7.4)

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8
Q

arterial bicarbonate (HCO3-)

A

22-26 mEq/L (24 mEq/L)

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9
Q

acidosis

A

pH<7.35

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10
Q

alkalosis

A

pH>7.45

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11
Q

What effect does increased HCO3 have on pH?

A

increases pH

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12
Q

What do the kidneys do to bicarbonate?

A

move to urine and reabsorb, along with secreting H+ to urine

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13
Q

What does GI do to HCO3?

A

secretes it and H+

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14
Q

What will vomiting and diarrhea cause to HCO3 levels?

A

decrease

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15
Q

Do anti-acids, lactic acid, lactate, and ketoacids change HCO3?

A

yes

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16
Q

What are metabolic disturbances?

A

changes in HCO3

17
Q

What is the balanced CO2/HCO3 equation?

A

CO2+H2O->H2CO3->H+ + HCO3

18
Q

How will increased CO2 change pHa?

A

lowers –> acidosis

19
Q

How will decreased CO2 change pHa?

A

increases –> alkalosis

20
Q

What is a respiratory disturbance in acid-base balance?

A

Anything that alters CO2 movement from the alveoli to the blood

21
Q

increased HCO3

A

metabolic increased pH (alkalotic)

22
Q

decreased HCO3

A

metabolic decreased pH (acidic)

23
Q

increased CO2

A

respiratory decreased pH (acidic)

24
Q

decreased CO2

A

respiratory increased pH (alkalotic)