acid base imbalane Flashcards
why is normal pH critical to survival?
enzymes are protens which ar sensitive to pH as it will easily damage them by denaturing. Enxymes must retain their shape lock and key in order to catalyze reactions. Enxymes are very important for bodily fx
how is ph measured clinically
arterial blood gas lab values
what information does a ph measured clinically give? how would this be obtained
gases, ph- this shows respiratory function and metabolic function
taken from venous blood
ph is a measure of?
hydrogen ion concentration
low ph=
high ph=
0-7=acidic
high=7-14 basic
alkalosis=
ph >7.45
acidosis=
ph
what are the 4 types of acid base imbalances
metabolic acidosis and alkalosis
respiraotry acidosis and alkalosis
how does the body address an acid base imbalance?
buffering.
how can metabolic be distinguihed from respiratory
if there is involvement of carbonic acid (h2c03)
how do you measure H2C03?
you cant really as it is too volatile. They measure the amount of C02 by PC02
what is PCO2
partial pressure of \C02
is it the amoun of HC03- or dissolved H2C03=H+HC03-)that determines ph?
no, it is the ratio of them
when the ratio is 20 HC03 to 1 C02 it can remain normal
carbonic acid-bicarbonate buffer system
C02 + H20=H2\C03=H+ + HC03-
(principal buffer system in ECF)
carbonic acid is transported in the body as carbaminohemoglobin, a dissolved gas, and as bicrabonate.
volatile acids in the body are eliminated by
the lungs (h2C03)
