Acid Base Balance I Flashcards
What is the effect on pH if hydrogen ion concentration increases
pH decreases
What is the pH of arterial blood
7.45
What is the pH of venous blood
7.35
What is pH sensitive
ion channel function
Why is potassium regulated within narrow limits
regulate the excitability of cells and membrane potential
What is affected by fluctuations in H+ levels
enzyme activities, potassium levels, excitability of muscle and nerves
Name an alkali pH value in the body
pancreatic secretions
Name an acidic pH value in the body
gastric secretions
What does metabolism generate
carbon dioxide
What is the pH of carbon dioxide
acidic
break down of what…. can generate hydrogen ions
proteins
What systems are involved with acid base balance
blood and tissue buffers, respiration, and renal
Which system is the fastest to react
blood and tissue buffers
Which system is the only mechanism for extrusion of acid/alkali
renal system
How does the respiratory system help with acid base balance
changes CO2 levels in the body
Where are buffers for acid base balance present
blood, extracellular fluid, intracellular fluid, urine
Name some examples of buffers
haemoglobin, bicarbonate, inorganic phosphate
What is the most important buffer
bicarbonate
What diseases might cause respiratory acidosis
asthma attack, emphysema and COPD
What happens when there is too much carbon dioxide in the body
pH becomes more acidic, bicarbonate concentration is high