Acetylation Flashcards
1
Q
What is required for Acetylation to occur?
A
A compound that can donate an acetyl group e.g. Acetyl coenzyme A
2
Q
How does an Acetyl group look like?
A
COCH3 (google image)
3
Q
What are the common groups conjugated?
A
OH, NH2
4
Q
What happens in Acetylation?
A
An acetyl group is conjugated to the molecule- substituted instead of NH2 or OH
5
Q
Is there genetic Variations in some acetyl transferases?
A
Yes- there are slow and fast acetyl transferases and the frequency varies with race: 60% of caucasians are slow acetylators, 95% of eskimos are fast acetylators.
6
Q
What drug is an example of Acetylation?
A
Procainaminde
