acetaminophen Flashcards
1
Q
maximum dose
A
3 g/day
2
Q
toxicity occurs at
A
7-10 g/day
3
Q
signs of toxicity
A
initial flu-like symptoms
liver failure
4
Q
antidote to toxicity
A
N-acetylcysteine
5
Q
toxic doses consume available..
A
glutathione
6
Q
consuming of glutathione causes a buildup of
A
toxic NAPQI
7
Q
NAPQI
A
minor product of acetaminohen metabolism
8
Q
alcohol can increase acetaminophen toxicity by inducing
A
CYP450 enzymes
