ACE Review - Rheum Flashcards

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1
Q

Questions.

A

Answers.

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2
Q

Most common finding in SLE

A

Asymptomatic pericarditis.

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3
Q

SLE Arrythima

A

Sinus tach, afib, av block

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4
Q

Hydroxychloroquine tx of SLE causes what

A

QT prolongation

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5
Q

SLE vascularity?

A

Increase atherosclerosis 2ndry to immune mediated and increased c reactive protein.

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6
Q

Methotrexate of SLE causes what.

A

Pulm infiltrates.

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7
Q

Cyclophosphamide of SLE Tx causes what

A

Renal insufficiencies.

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8
Q

can you give neuromusclar blocking drugs non depolarizers for myotonic dystrophy

A

yes..they are not contraindicated

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9
Q

what worry do we have about myotonic dystrophy patients

A

myotonic episodes

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10
Q

what can potentiate a myotonic episode..hyperthermia vs hypothermia?

A

hypothermia, bc shivering can precipitate it

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11
Q

why is regional anesthesia better for myotonic patients?

A

because your use of opiods and respiratory depressants can be decreased. Myotonic patients have been shown to have an increased sensitivity to opiods and narcotics

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12
Q

what is a myotonic episodde

A

period of prolong muscle contracture

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13
Q

what is the hereditary of myotonic dystrophy

A

it is autosomal dominant

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14
Q

what happens to the muscles in myotonic dystrophy

A

muscles become wasted

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15
Q

what other organ is affected in myotonic dystrophy

A

cardiac and smooth muscle are affected

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16
Q

what anesthetic drug is a risk factor for causing myotonia in myotonic dystrophy

A

succinylcholine

17
Q

what is another drug that may cause myotonia in myotonic dystrophy

A

etomidate

18
Q

besides meds, what else can cause myotonia in myotonic dystrophy

A

hypothermia and direct surgical stimuli to the muslcle

19
Q

can you use anesthetic gases to treat the myotonia

A

it can be attempted, but the cradiac conditions in these patients might not tolerate the gases

20
Q

what is the treatment for myotonic dystrophy myotonia

A

quinine, procainamide, or phenytoin

21
Q

what can surgeons do to a muslcle that is in myotonia

A

local anesthesia infiltration may relax the muscle

22
Q

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A

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23
Q

What cardiac problems are in sle

A

Atherosclerosis, pericarditis, mitral and aortic valve thickening leading to stenosis/regurge,

24
Q

What pulm issues occur with sle

A

Pleuritic chest pain,Pleural effusions, interstitial lung disease, pulmonary hypertension

25
Q

Why do sle get pulm hypertension

A

Because of recurrent pulmonary embolisms

26
Q

What happens to sle kidneys

A

Nephrotic syndromes

27
Q

What blood disorders are associated with sle

A

Pancytopenia…they also have antiphospholipid antibodies and are at increase risk for emboli