ACE Review - Rheum Flashcards
Questions.
Answers.
Most common finding in SLE
Asymptomatic pericarditis.
SLE Arrythima
Sinus tach, afib, av block
Hydroxychloroquine tx of SLE causes what
QT prolongation
SLE vascularity?
Increase atherosclerosis 2ndry to immune mediated and increased c reactive protein.
Methotrexate of SLE causes what.
Pulm infiltrates.
Cyclophosphamide of SLE Tx causes what
Renal insufficiencies.
can you give neuromusclar blocking drugs non depolarizers for myotonic dystrophy
yes..they are not contraindicated
what worry do we have about myotonic dystrophy patients
myotonic episodes
what can potentiate a myotonic episode..hyperthermia vs hypothermia?
hypothermia, bc shivering can precipitate it
why is regional anesthesia better for myotonic patients?
because your use of opiods and respiratory depressants can be decreased. Myotonic patients have been shown to have an increased sensitivity to opiods and narcotics
what is a myotonic episodde
period of prolong muscle contracture
what is the hereditary of myotonic dystrophy
it is autosomal dominant
what happens to the muscles in myotonic dystrophy
muscles become wasted
what other organ is affected in myotonic dystrophy
cardiac and smooth muscle are affected
what anesthetic drug is a risk factor for causing myotonia in myotonic dystrophy
succinylcholine
what is another drug that may cause myotonia in myotonic dystrophy
etomidate
besides meds, what else can cause myotonia in myotonic dystrophy
hypothermia and direct surgical stimuli to the muslcle
can you use anesthetic gases to treat the myotonia
it can be attempted, but the cradiac conditions in these patients might not tolerate the gases
what is the treatment for myotonic dystrophy myotonia
quinine, procainamide, or phenytoin
what can surgeons do to a muslcle that is in myotonia
local anesthesia infiltration may relax the muscle
xxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxx
What cardiac problems are in sle
Atherosclerosis, pericarditis, mitral and aortic valve thickening leading to stenosis/regurge,
What pulm issues occur with sle
Pleuritic chest pain,Pleural effusions, interstitial lung disease, pulmonary hypertension
Why do sle get pulm hypertension
Because of recurrent pulmonary embolisms
What happens to sle kidneys
Nephrotic syndromes
What blood disorders are associated with sle
Pancytopenia…they also have antiphospholipid antibodies and are at increase risk for emboli
