ACE Review - Liver

Question 1

What happens to cardiac output in liver patients

Answer 1

Increase cardiac output

Question 2

What happens to svr in liver patients

Answer 2

Decrease svr

Question 3

is ffp pooled from one or many donors

Answer 3

one donor

Question 4

do you need abo compatibility for ffp transfusion

Answer 4

yes

Question 5

do you need crossmatching compatibility for ffp

Answer 5

no

Question 6

if a pt is blood type a, what kind of ffp can they get

Answer 6

they can get type a or type o

Question 7

if a patient is blood type b, what kind of ffp can they get,

Answer 7

type b or type o

Question 8

if a pt is type ab, what kind of ffp can the pt get

Answer 8

any type

Question 9

if the pt is type o, what kind of ffp can they get

Answer 9

only type o

Question 10

does Rh factor matter in giving ffp

Answer 10

in males, it does not matter, but in females, it does matter

Question 11

why does rh factor in ffp matter for female

Answer 11

because giving a Rh negative female ffp w/ Rh factor may cause alloimmunization and this may cause problems with their future pregnancies if they have a fetus that is Rh positive

Question 12

after thawing ffp, how much time far out can u still use the blood

Answer 12

1d

Question 13

what are indications to give ffp for drug reversal

Answer 13

warfarin

Question 14

what clotting factor deficiency is ffp admin indicated for

Answer 14

factor v and viii deficiency

Question 15

between factor v and viii, which has a stronger indication for ffp transfusion

Answer 15

factor v because factor viii not only is available in ffp, but factor viii concentrates as well

Question 16

besides factor v and viii deficiency, wat other coagulopathic condition needs ffp for administration

Answer 16

thrombottic thrombocytopenia purpura…these pts lack the enzyme adam ts that cuts polymers of vwf…vwf is provided by ffp

Question 17

what treatment sounds paradoxical use for ffp

Answer 17

antithrombin III deficiency…when giving heparin and anticoagulation is not achived…this is because no antithrombin III is available for heparin to work

Question 18

if pt is on plavix…does ffp help reverse?

Answer 18

no…platelets are the treatment

Question 19

port wine urine

Answer 19

porphyria

Question 20

what are other symptoms of porphyria

Answer 20

abdominal pain, neuropsychic attacks, autonomic instabile

Question 21

what are the porphyrias split into

Answer 21

acute and non acute

Question 22

what is the most common acute porphyria

Answer 22

acute intermitten porphyria

Question 23

what is the cause of acute intermitten porphyria

Answer 23

deficient enzyme called PBC deaminase needed for heme synth

Question 24

what happens when PBC deaminase is deficient

Answer 24

porphyria molecule builds up

Question 25

what drugs are contraindicated in acute intermittent porphyria

Answer 25

barbs (thiopental, methylhexital) and etomidate and PROBABLY nifedipine