Abx Info Flashcards
E. coli Abx
all BUT: penicillin diclox vanc clinda metro
E. coli TEM-1 Abx
same as E. coli, EXCEPT ALSO NO amox/amp
all BUT: penicillin, diclox, vanc, clinda, metro, amox/amp
E. coli ESBL Abx
same as E. coli TEM-1, but ALSO NO cephalosporins and all others are +/- (all BUT: penicillin, diclox, vanc, clinda, metro, amox/amp, cephalos)
Klebsiella SHV-1 Abx
same as E-coli TEM-1 (all BUT: penicillin, diclox, vanc, clinda, metro, amox/amp)
Klebsiella KPC Abx
ONLY: chloramph amino cipro levo moxi nitro
Bacteriodes fragilis Abx
ONLY: amox/clav pip/tazo carbapenems clinda +/- chloramph metro
Name the gram (-) rods.
- Bacteriodes fragilis (sorta)
- E. coli (and E. coli TEM-1 and ESBL)
- Klebisiella (SHV-1 and KPC)
- Pseudomonas aeruginosa
Name the gram (+) cocci.
Staphs (MSSA and MRSA)
Streps (pyogenes, pneumoniae, viridans)
Enterobacter
VRE
Name the gram (+) rods.
C. diff, Clostriduim
Name the anaerobes.
C. diff, Clostridium
Name the weird ones (no cell wall, intracellular).
Chlamydia, Mycoplasma
Name the gram (-) cocci.
N. gonorrhoeae
N. gonorrhoeae Abx
ONLY:
3rd gen cephalosporin (ceftriaxone)
+/- macro
+/- tetracycline
Chlamydia Abx
(same as Mycoplasma) ONLY: macro tetra chloramph cipro/levo/moxi
Mycoplasma Abx
(same as Chlamydia) ONLY: macro tetra chloramph cipro/levo/moxi
MRSA Abx
ONLY:
vanc
nitro
C. diff Abx
ONLY:
vanc
metro
MSSA Abx
all BUT: penicillin amox/amp chloramph amino metro
VRE Abx
ONLY:
chloramph +/-
nitro +/-
Entero Abx
ONLY: penicillin amox/amp amox/clav pip/tazo vanc nitro
Viridans strep Abx
all BUT:
amino
metro
cipro
S. pyogenes Abx
all BUT:
metro
S. pneumonia Abx
all BUT:
amino
metro
Pseudomonas Abx
ONLY: pip/tazo 3rd and 4th gen cephalo (Ceftazidimine and Cefepime) imp/dori/mero amino cipro levo
Penicillin treats which bugs?
streps and entero (gram +)
Dicloxacillin treats which bugs?
streps and MSSA (gram +)
Amox/amp treats which bugs?
strep, entero, E. coli (gram + and -)
Amox/clav treats which bugs?
same as amox/amp WITH MSSA, Klebsiella, bacteriodes (strep, MSSA, entero, E. colis, Klebsiella SHV-1, bacteriodes) (gram +, -, and anaerobes)
Pip/tazo treats which bugs?
same as pip/tazo WITH pseud (strep, MSSA, entero, E. colis, Klebsiella SHV-1, bacteriodes, pseudomonas) (gram +, -, and anaerobes)
1st gen Cephalosporins (cephalexin) treats which bugs?
normal gram + including MSSA, normal gram -
1st gen Cephalosporins (cephazolin) treats which bugs?
normal gram + including MSSA, normal gram -
2nd gen Cephalosporins (cefuroxime) treats which bugs?
normal gram + including MSSA, normal gram -, Clostridium perfringins
3rd gen Cephalosporins (Ceftriaxone) treats which bugs?
normal gram + including MSSA, normal gram -, Clostridium perfringins, AND N. gonorrhea
3rd gen Cephalosporins (Ceftazidime) treats which bugs?
normal gram + but not really MSSA, normal gram -, Clostridium perfringins AND pseudomonas
4th gen Cephalosporins (cefepime) treats which bugs?
normal gram + including MSSA, normal gram -, AND pseudomonas
Name the 2 carbapenems.
- ertapenem
2. imip/dori/mero-penem
Ertapenem treats which bugs?
normal gram + including MSSA, gram -, clostiridum perfringes, Bacteriodes (same as Imip/dori/mero-penem but NO pseudomonas)
Imip/dori/mero-penem treats which bugs?
same as Ertapenem but ADD pseudomonas (normal gram + including MSSA, gram -, clostiridum perfringes, Bacteriodes, pseudomonas)
Vanc treats which bugs?
all gram + INCLUDING MSSA and MRSA, Enterococcus; NO gram -; both Clostridiums (incl C. diff!)
Which drugs are the Beta-lactams?
penicillins, cephalosporins, and carbapenems
Which drugs are the cell wall synthesis inhibitors?
all the Beta-lactams (penicillins, cephalosporins, and carbapenems) AND vanc
Which drugs are the protein synthesis inhibitors?
macro tetracycline clinda chloramphenicol amino
What are the 3 fluoroquinolones?
- cipro
- levo
- moxi
How are levo and moxi different?
levo treats pseudomonas
How is cipro different from levo?
cipro isn’t as good at gram +
Which bugs will cipro treat?
sorta gram +, very gram -, pseudo, weird ones (chlamydia and mycoplasma)
Which bugs will levo treat?
gram +, very gram -, pseudo, clost, perfringens, weirdos
Which bugs will moxi treat?
gram +, very gram -, clost, perfringens, weirdos (same as levo but NO pseudomonas)
What bugs does nitrofuantoin treat?
very gram + including MSSA and MRSA with a little bit of VRE; very gram - (good at E. coli)
What bugs does metronidazole treat?
ONLY C. diff, C. perfringens, and Bacteriodes fragilis (the anaerobes)
Which drug only treats the anaerobes?
metro
Which drugs treat the weirdos (chlamydia and mycoplasma)?
macrolides, tetracycline, chloramphenicol, all fluoroquinolones (cipro, levo, moxi)
Vanc is N.O.T. trouble free.
nephrotoxicity, Ototoxicity, Thrombophlebitis
Protein synth. inhibitors: Buy AT 30, CCEL at 50.
AT = aminoglycosides (cidal); tetracycline (static)
CCEL= Chloramphenicol, Clindamycin (static)
Erythromycin (a macrolide- static)
Linezolid (varies)
Which drugs should not be taken with milk, antacids, or iron?
tetra, fluoroquinolones
Which drugs are assoc. with superinfections?
C-FACT
Cephalosporins (2nd-3rd), Fluoroquinolones, Amox/amp, Clindamycin, Tetracycline
Which drug is mostly just used to treat bladder/UTIs?
nitro
Which drug can cause pseudomembranous colitis?
clinda
Which drug increases the Q-T interval?
fluoroquinolones
Which drugs are renally cleared?
FAT CCVP
- fluoroquinolones
- amino
- tetra
- carbapanems
- cephalosporins
- vanc
- penicillin
Which drugs are hepatically excreted?
CRIMM
- clinda
- rifampin
- isoniazid
- metro
- macro
Which drug induces P450?
rifampin
Which drug inhibits P450?
the macrolides
What does rifampin treat?
Tb
What does Isoniazid treat?
Tb