Abx Flashcards

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1
Q

Penicillin target and class

A

cell wall

beta lactam

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2
Q

Methicillin target and class

A

cell wall

beta lactam

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3
Q

Cloxacillin target and class

A

cell wall

beta lactam

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4
Q

Oxacillin target and class

A

cell wall

beta lactam

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5
Q

Ampicillin target and class

A

cell wall

beta lactam

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6
Q

Amoxacillin target and class

A

cell wall

beta lactam

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7
Q

Cephalosporin target and class

A

cell wall

beta lactam cephem

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8
Q

Imipenem target and class

A

cell wall

beta lactam carbapenem

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9
Q

Aztreonam target and class

A

cell wall

beta lactam monobactams

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10
Q

Vancomycin target and class

A

cell wall

non-beta lactam glycopeptide

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11
Q

Bacitracin target and class

A

cell wall

topical

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12
Q

Isonazid target and class

A

cell wall

anti-TB

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13
Q

Rifampin target and class

A

RNA synthesis

rifamycin

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14
Q

Rifabutin target and class

A

RNA synthesis

rifamycin

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15
Q

Lincomycin target and class

A

protein synthesis

lincosamides

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16
Q

Clindamycin target and class

A

protein synthesis

lincosamides

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17
Q

Erythromycin target and class

A

protein synthesis

macrolides

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18
Q

Clarithromycin target and class

A

protein synthesis

macrolides

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19
Q

Azithromycin target and class

A

protein synthesis

macrolides

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20
Q

Streptomycin target and class

A

protein synthesis

aminoglycosides

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21
Q

Gentamycin target and class

A

protein synthesis

aminoglycosides

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22
Q

Tobramycin target and class

A

protein synthesis

aminoglycosides

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23
Q

Quinupristin target and class

A

protein synthesis

streptogramins

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24
Q

Dalfopristin target and class

A

protein synthesis

streptogramins

25
Q

Tigecycline target and class

A

protein synthesis

glycyclines

26
Q

Tetracycline target and class

A

protein synthesis

tetracycline

27
Q

Doxycycline target and class

A

protein synthesis

tetracycline

28
Q

Minocycline target and class

A

protein synthesis

tetracycline

29
Q

Zyvoz target and class

A

protein synthesis

oxazolidinone

30
Q

Sivextro target and class

A

protein synthesis

oxazolidinone

31
Q

Nystatin target and class

A

cell membrane

polyvene

32
Q

Amphotericin target and class

A

cell membrane

polyvene

33
Q

Chlorhexidine target and class

A

cell membrane

antispetic mouthwash

34
Q

Polymyxin target and class

A

cell membrane

topical

35
Q

Daptomycin target and class

A

cell membrane

lipopeptide

36
Q

Metronidazole target and class

A

DNA synthesis

nitroimidazole

37
Q

Ciproflaxocin target and class

A

DNA synthesis
quinolones
fluoroquinolones

38
Q

Sulfadiazine target and class

A

metabolism

sulfonamides

39
Q

Trimethoprim target and class

A

metabolism

sulfonamides

40
Q

Beta lactam MOA

A

interferes with cross linking of peptidoglycan

41
Q

Non-beta lactam glycopeptide MOA

A

cell wall synthesis inhibitor

42
Q

Bacitracin MOA

A

stops cell wall synthesis

43
Q

Isoniazid MOA

A

inhibits mycolic acid synthesis

44
Q

Rifamycin MOA

A

inhibits transcription initiation

45
Q

Lincosamides MOA

A

translation inhibitor, blocks 50S ribosome, and inhibits translocation

46
Q

Macrolides MOA

A

translation inhibitor binds 50S ribosome

47
Q

Aminoglycosides MOA

A

translation inhibitor blocks 30S ribosome

48
Q

Macrocyclics MOA

A

RNA polymerase inhibitor in C. diff only

49
Q

Streptogramins MOA

A

binds 50S ribosome

50
Q

Glycocyclines MOA

A

block 30S ribosome

51
Q

Tetracyclines MOA

A

translation inhibitor, blocks 30S ribosome, stops tRNA binding

52
Q

Oxazolidinone MOA

A

block tRNA binding to ribosome

53
Q

Polyvene MOA

A

binds ergosterol in fungal cell membrane

54
Q

Chlorhexidine MOA

A

membrane disruption

55
Q

Polymyxin MOA

A

detergent action

56
Q

Lipopeptide MOA

A

disrupts ionic concentration gradients

57
Q

Nitroimidazole MOA

A

strict anaerobes are sensitive and some protozoa

58
Q

Quinolone and fluoroquinolone MOA

A

inhibit DNA gyrase- transcription inhibitor

59
Q

Sulfonamides MOA

A

blocks folic acid synthesis- need folate for DNA