Absorption II Flashcards

1
Q

Vitamin B12 and biliary salts are absorbed in

A

Terminal ilion

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2
Q

All absorbed molecules go to

A

Portal circulation

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3
Q

Lipids and liposoluble vitamins go to

A

Lymphatic circulation

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4
Q

Lumbar and hepatic lymphatic systems drain into

A

Cisterna chyli

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5
Q

Function of cisterna chyli

A

Accumulate lymph and recirculate them

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6
Q

2 systems that drain the lymphatics

A

Thoracic duct, main one

Left subclavian artery

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7
Q

Main elements of the lymph

A

Chylomicrons and immune cells

But carbohydrates and protein from drainage of capillary network are also included

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8
Q

L secreted along length of digestive system

A

7L

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9
Q

L passing through digestive tube in 24h

A

9L

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10
Q

mL of H2O eliminated daily

A

200 mL

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11
Q

What part is in charge of absorbing water for feces to be solid

A

Colon

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12
Q

Most of nutrients absorbed by

A

Small intestine

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13
Q

Colon absorbs

A

Water and vitamins

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14
Q

B12 absorption in

A

Terminal ilion

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15
Q

What protects Vitamin B12 from digestion

A

Haptocorrin HC

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16
Q

What proteolyses HC (Haptocorrin) in duodenum

A

Pancreatic proteoases

17
Q

After HC has been proteolysed, VitB12 binds to

A

Intrsinsic factor, IF

18
Q

What produced IF, intrinsic factor

A

Gastric parietal cels

19
Q

IF + VitB12 go to terminal ileum where there is a high density of

A

Cubilin, which is a receptor of the microvilli

20
Q

Iron in diet can be either in

A

Free form of bound to a heme group

21
Q

Free iron is in the form of

A

Ferric iron 3+

22
Q

What can only be absorbed by DMT1

A

Ferrous form of iron

23
Q

Ferric iron –> ferrous iron through

A

Ferroductase

24
Q

Ferroportin and hephaestin function

A

Release ferrous iron and transform it into ferric iron

25
Q

Ferric iron transported to liver and bone marrow through

A

Transferring

26
Q

Iron accumulates in tissues thanks to

A

Ferritin

27
Q

Transcellular active absorption of calcium through

A

Ca++ channels

28
Q

Endocytosis absorption of Ca++

A

Through endocytosis + fusion w/ lysosomes and exocytosis

29
Q

Paracellular passive absorption of Ca++

A

Through diffusion

30
Q

How is Ca++ stored in cells

A

Due to calbindin

31
Q

Function of Vitamin D in calcium absorption and storage

A

Vitamin D increases calbindin levels