Absorption Flashcards
products of digestion
amino acids, glucose, monoglycerides and fatty acids
assimilation
use of products of digestion (for protein synthesis, respiration and formation of phospholipid bilayer)
structure of the ileum in terms of absorption
mucosal layer contains folds, with contain further folds in the epithelial cell membrane
how do villi and microvilli increase efficiency of absorption?
increase SA available for insertion of carier proteins to increase rate of absorption
how does circulating blood increase absorption efficiency?
maintains concentration gradient by transporting products of digestion away
how does a thin ileum wall increase absorption efficiency?
decreases distance for diffusion so increases rate of absorption
how does a muscle layer increase absorption effiency?
maintain diffusion gradient by “pushing” molecules agains the villi
where does absorption take place from and to?
From ileum lumen into:
capillary network
lacteal
function of the Golgi body in absorption
- modifies/processes triglycerides
- combines them with proteins to form chylomicrons
- packages chylomicrons/triglycerides for release by exocytosis
3 mechanisms for absorption
diffusion, active transport ad osmosis
deamination
process of removing an amino group from an amino acid
assimilation of glucose
glucose taken up for aerobic respiration to produce ATP
what happens to excess glucose?
converted to glycogen or fat stores and stored in the liver
assimilation of fats
used to form the phospholipid bilayer of cells
what happens to excess fats?
stored as adipose tissue
why can’t we store excess amino acids?
they are toxic in high concentrations due to the nitrogen they contain
5 steps of absorption of lipids
- monoglycerides ad fatty acids are released from micelles and enter the epithelial cells of mucosal tissue by simple diffusion
- mooglycerides and fatty acids reform triglycerides
- in golgi body, triglycerides are combined with proteins to form chylomicrons
- chylomicrons released from epithelial cells by exocytosis and enter the lacteal
- transported in lymph away from ileum and enter blood at thoracic duct
why from chylomicrons?
surround trigycerides with a protein so soluble n water so can be transported in blood plasma
4 steps of absorption of glucose/a.a.
- Na+/K+ntiporter actively transported NA+out epithelial cellinto tissue fluid and K+ into epithelial cell
- Na+ ion concentration loered inside cell, below that of gut lumen, creating a concentration gradient
- Na+ ions passively transported into cell by facilitated diffusion via a symporter, which prvides energy to pull glucose/a.a. with them actively
- Glucose/a.a. concentration increases above that of capillary so they’re transforted by facilitated diffusion into TF, via carrier proteins, down a concentration gradient