ABORTION Flashcards

1
Q

Abortion

A

Spontaneous or induced termination of pregnancy before fetal viability

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2
Q

Abortion

A

pregnancy termination before 20 weeks’ gestation

OR

fetus born weighing < 500 g

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3
Q

Spontaneous Abortion

A
threatened
inevitable
incomplete
complete
missed abortion
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4
Q

> 80 % of spontaneous abortions occur within the

A

first 12 weeks

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5
Q

No identifiable embryonic elements

A

anembryonic miscarriage

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6
Q

Often display a developmental abnormality of the embryo, fetus, yolk sac, and, at times, the placenta

A

embryonic miscarriages

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7
Q

75 % of chromosomally abnormal abortions occurred by

A

8 weeks’ gestation

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8
Q

Most frequently identified chromosomal anomaly in the 1st trimester

A

Autosomal Trisomy

trisomies of chromosomes 13, 16, 18, 21 , and 22 - most common

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9
Q

Single most frequent specific chromosomal abnormality

A

Monosomy X (45,X) (Turner Syndrome)

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10
Q

Associated with hydropic or molar pregnancy

A

Triploidy

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11
Q

Presumed when bloody vaginal discharge or bleeding appears through a closed cervical os during the first 20 weeks

A

Threatened Abortion

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12
Q

The most predictive risk factor for pregnancy loss

A

Bleeding

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13
Q

serum progesterone concentrations that suggest a dying pregnancy

A

< 5 ng/mL

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14
Q

Used to locate the pregnancy and determine viability

A

Transvaginal sonography

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15
Q

Bleeding that follows partial or complete placental separation and dilation of the cervical os

A

Incomplete Abortion

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16
Q

History of heavy bleeding, cramping, and passage of tissue or a fetus

During examination – closed cervical os

A

Complete Abortion

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17
Q

Describes dead products of conception that were retained for days, weeks, or even months in the uterus with a closed cervical os

A

Missed Abortion

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18
Q

Nonviable pregnancy without vaginal bleeding, uterine cramping or cervical dilation

A

Missed Abortion

19
Q

Recurrent Abortion

A

≥ 3 losses at < 20 weeks OR with a fetal weight < 500 grams

American Society for Reproductive Medicine (2008)
≥ 2 failed clinical pregnancies confirmed by either sonographic or histopathological examination

20
Q

Refers to multiple losses in a woman who has never delivered a live born

A

Primary RPL

21
Q

Refers to multiple pregnancy losses in a patient with a prior live birth

A

Secondary RPL

22
Q

Midtrimester Abortion

A

Extends from the end of the 1st trimester until the fetus weighs ≥ 500 g or gestational age reaches 20 wks

23
Q

Risk Factors For Second-Trimester Abortion

A

race
ethnicity
prior poor obstetrical outcomes
extremes of maternal age

24
Q

Recommended for women with prior preterm birth

A

Cervical length screening

25
Q

Funneling

A

Ballooning of the membranes into a dilated internal os but with a closed external os

26
Q

Contraindications to Cerclage

A

bleeding
contractions
ruptured membranes

27
Q

Simpler procedure and most commonly used vaginal cerclage

A

McDonald

28
Q

Complications of Cerclage

A

membrane rupture
preterm labor
hemorrhage
infection

29
Q

Medical or surgical termination of pregnancy before the time of fetal viability

A

Induced Abortion

30
Q

number of abortions per 1000 live births

A

abortion ratio

31
Q

number of abortions per 1000 women aged 15 to 44 years

A

abortion rate

32
Q

Medical And Surgical Disorders That Are Indication For Termination Of Pregnancy

A

persistent cardiac decompensation (with field pulmonary hypertension)

advanced hypertensive vascular disease or diabetes

malignancy

to prevent birth of a fetus with a significant
anatomical, metabolic, or mental deformity - THE MOST FREQUENT INDICATION CURRENTLY

33
Q

hygroscopic dilators (osmotic dilators)

A

Devices that draw water from surrounding tissues and expand to gradually dilate the endocervical canal

For ripening

34
Q

Side effects of Misoprostol

A

fever
bleeding
gastrointestinal side effects

35
Q

Antiprogestin; effective cervical-ripening agent

A

Mifepristone

36
Q

Prevent postabortal infection after a first- or second-trimester surgical evacuation

A

prophylactic Doxycycline

37
Q

Transcervical approach to surgical abortion

cervix is first dilated and then products of conception are evacuated

A

Vacuum Aspiration

38
Q

sharp dilation and curettage (DC)

A

Contents are mechanically scraped out solely by a sharp curette

currently NOT recommended for pregnancy evacuation due to greater blood loss, pain, and procedural time

39
Q

Lies within connective tissue lateral to the uterosacral and cardinal ligaments and supply cervix, vagina, and uterus

A

Frankenhauser plexus

40
Q

Risk factors for abortion complication

A
operator inexperience
prior cervical surgery or anomaly
adolescence
multiparity
advanced gestational age
41
Q

3 Medications Used Alone Or In Combination in Medical Abortion

A

Mifepristone – augments uterine contractility by reversing progesterone-induced myometrial quiescence

Methotrexate - acts on trophoblast and halts implantation

Misoprostol - directly stimulates the myometrium

42
Q

Symptoms following Misoprostol (common w/n 3 hrs)

A

vomiting
diarrhea
fever
chill

bleeding and cramping

43
Q

Indications for uterine evacuation in the 2nd trimester

A

fetal anomaly or death
maternal health complications
inevitable abortion
desired termination