Abnormality Flashcards
Schizophrenia and Psychotic disorders
Include a range of psychotic disorders that affect all aspects of a person’s thinking, emotions, actions, along with a major break from reality.
The personal, social and occupational functioning deteriorate because of disturbed thought process, unusual emotions and motor abnormalities.
DSM definition
Schizophrenic spectrum and psychotic disorders as sharing one or more of the following: e.g. delusions, hallucinations, disorganised thoughts or negative symptoms e.g. loss of speech
When diagnosed?
DSM: two symptoms for at least one month one must be delusions, hallucinations or disorganised thoughts/speech
Types of Psychotic Disorders
Schizotypal: difficulty developing emotionally meaningful relationships with others and showing extreme coldness and flat affect
Substance induced psychotic disorder: a psychiatric disorder featured by delusions and/or hallucinations during or soon after substances intoxication or withdrawal
Case Study
Conrad, male aged 23.
First episode aged 22 while on holiday, later diagnosed with schizo-affective disorder.
At first he was reluctant to seek treatment as he was unsure of recovery. He spent eight months following diagnosis in a psychiatric hospital. Conrad eventually found the right drug treatment but struggles with maintaining a healthy weight.
Delusional Disorder (inc. types and diagnosis)
Characterised by persistent delusions but whose other behaviours are ‘normal’. There is an absence of the other psychotic symptoms of schizophrenia such as hallucinations, disorganised speech or negative symptoms.
Types:
Erotomaniac: belief that another person is in love with them
Grandiose: they are convinced they have a great unrecognised skill or status
Jealous: belief their partner is being unfaithful
Symptoms for at least one month and be unrelated to physiological effects of substance use.
Freeman Aim
To investigate the use of virtual reality in assessing symptoms of shizophrenia
Freeman Procedure
- 200 non-clinical participants
- Multiple measures: level of paranoia, emotional distress as well as social/cognitive traits. Simulator-sickness questionnaire was given before and after the simulation.
- Participants entered a 4 min virtual reality journey of either a library or underground train scene where the person walks/rides in the presence of other neutral avatars.
- After completion, persecutory thinking was measured alongside a VAS and an assessment of immersion in the environment
Freeman results
Those who scored highly on the assessment of paranoia experienced high levels of persecutory ideation during VR.
Gottesman and Shields Aim:
Genes or particular combinations of genes are passed on to offspring which may cause the disorder to develop.
Carry out a twin study to look at the genetic inheritance of schizophrenia. Symptoms of schizophrenia e.g. psychosis have known genetic origins and are known as ‘endophenotypes’ meaning it is possible to inherit them.
Gottesman and Shields Procedure:
- 57 pairs of twins were used - 24 sets of MZ twins and 33 DZ twins.
- Researchers interviewed the patients alongside their twins, some of whom also had a diagnosis of schizophrenia.
- Participants also undertook cognitive tests e.g. object sorting.
- Case summaries of each participant were also independently evaluated by external judges.
Gottesman and Shields Findings
50% MZ twins shared schizophrenia status - DZ twins, 9%.
For MZ twins, if the illness of one twin was severe, the other twin was much more likely to have schizophrenia.
Biochemical (dopamine hypothesis) explanation of Schizophrenia
- Brains of those with schizophrenia produce more dopamine than those without. Hypothesis identified a link between excessive amounts of dopamine and positive symptoms of schizophrenia.
- Supported by drug trials w/ participants diagnosed with and without schizophrenia. Amphetamines and cocaine are known to produce excess dopamine - increase in dopamine correlates with an increase in the reporting of hallucinations and delusions.
- Patients with Parkinson’s disease are often treated with synthetic form of dopamine, if their dosage is too high, it creates symptoms such as hallucinations.
Test for Dopamine Hypothesis
- Lindstroem et al. gave 10 people with schizophrenia and 10 people without L-Dopa (drug to increase dopamine) and found that those with schizophrenia absorbed the drug quicker.
Cognitive explanation of Schizophrenia
FRITH
Schizophrenia involves an abnormality of self-monitoring. Believed schizophrenia sufferers have problems with meta-representation e.g. failing to recognise hallucinations are just inner speech resulting in them attributing what they hear to someone else.
Also believed schizophrenia may be caused by a cognitive impairment which explains symptoms like disorganised thoughts.
An additional aspect was the patients may have a less developed TOM and so may develop delusions to try understand others’ actions.
Frith supporting procedure
Frith tested abnormality of self-monitoring with schizophrenic patients by asking if items read out loud were done so by themselves, an experimenter or a computer. Schizophrenic patients with incoherent speech performed worst at the task. Delusional thinking may arise from misinterpretation of perception.
Biochemical treatment of schizophrenia
Typical: Chlorpromazine reduce dopamine activity by blocking dopamine receptors. Reduces positive symptoms e.g. hallucinations and has calming effect.
Atypical: Clozapine block dopamine production and act on others e.g. serotonin. These are better for negative symptoms + treatment resistant
Research into effectiveness of drugs
Research into the effectiveness of drugs via randomised control trials, double-blind placebo controlled shows that 50% of those taking antipsychotic medication show significant improvement after 4-6 weeks - 30-40% show partial improvement and a small minority show 0 improvement (treatment-resistant schizophrenia).
ECT
ECT is a procedure done under general anaesthesia.
The treatment involves passing electricity through the brain to induce a brief seizure.
Patients undergo a course of ECT ranging from 6-12 sessions, often being given twice a week or at longer intervals to prevent relapse.
It is applied to the non-dominant hemisphere to reduce memory loss.
Rarely used as there is little evidence that it is more effective than other forms of therapy.
Token economy (Paul and Lentz) Aim
Investigated the effectiveness of a token economy on managing symptoms of schizophrenia. Token economy is based on the behaviourist principles of positive reinforcement for encouraging desirable behaviours. Believes symptoms occur as a result of a learned response - focuses on helping patients unlearn symptoms.
Paul and Lentz procedure
84 individuals from a psychiatric institution participated.
Over four and a half years, Paul and Lentz used an independent measures design to compare the outcomes of three different treatments: milieu therapy, traditional hospital management and a token economy.
Patients were given ‘tokens’ as a reward for appropriate behaviours e.g. self-care. The tokens could be exchanged for luxury items like clothing and cigarettes. Behaviour was monitored through time-sample observation, standardised questionnaire and individual interviews.
Paul and Lentz findings
Positive and negative symptoms were reduced.
Most effective reduction was found in catatonic behaviour and less successful for hallucinations/delusions.
97% of the token economy group were able to live independently in the community for 1.5-5 years compared to 71% in the milieu group and 45% in the hospital group.
Cognitive-behavioural therapy (Sensky) Definition and Aim
CBT is a talking therapy designed to help people change through recognising thoughts which underlie their behaviours.
Sensky used a RCT to compare the effectiveness of CBT with ‘befriending’ (one-to-one discussions about hobbies, sports, current affairs) with schizophrenia patients.
Sensky procedure
90 patients diagnosed with treatment-resistant schizophrenia.
Received an average of 19 sessions of CBT or befriending.
Randomly allocated and independent measures used.
Intervention delivered by experienced nurses. CBT treatment followed stages, first discussing emergence of their disorder before tackling specific symptoms. Patients kept voice diaries to record what they were hearing to generate coping strategies.
Ppts assessed by blind raters prior to treatment, at treatment completion and at a nine month follow-up. A number of standardised, validated assessment scales were used.
Sensky findings
Both groups showed a significant reduction in positive and negative symptoms. However, at the follow-up, the CBT group continued to improve in reduction of positive symptoms.
Define abnormal affect disorder
Abnormal affect disorders are classified as ‘mood disorders’ in the DSM-V.
This distinguishes them from brief feelings of sadness or joy.
Characteristics
Emotions are amplified beyond the normal ups and downs, in either extremely negative or positive directions which can persist for long periods of time.
Individuals may experience strong feelings of despair and emptiness or anger or euphoria.
Disorders of abnormal affect significantly impair the individual’s ability to function normally.
Unipolar depression
Type of affective disorder characterised by sadness and hopelessness for an extended period of time ranging from mild to moderate or severe.
This includes a lack of pleasure in most activities, weight changes, changes in sleep patterns, psychomotor agitation, fatigue, feelings of worthlessness and reduction in ability to concentrate.
To be diagnosed, you must have ⅝ symptoms for at least two weeks:
Weight loss/gain
Insomnia/hypersomnia
Loss of energy/tiredness
Agitated depression
Loss of interest in previously enjoyed activities
Guilt
Reduced ability to think/concentrate
Suicidal thoughts
Mania (bipolar):
Affective disorder characterised by episodes that alternate between mania and depression that cannot be accounted for.
Mania may include feelings of euphoria, rage or irritability for a long period of time.
Behavioural symptoms include becoming easily distracted, having racing thoughts, sudden interest in new activities, overconfidence, speaking quickly, sleeping less, engaging in risky behaviours.
Measures: Beck Depression Inventory
- Psychometric test
- 21 item self-report measure
- assesses the attitudes and symptoms of depression.
- Each item has at least four statements (four point scale 0-3)
- Respondee must choose one that best fits how they have been feeling as of recent.
- The total score determines the severity of the disorder: 10 is the minimum for mild depression, 19-29 for moderate, and 30 or more for severe there are a total of
- Two revised versions since
- An example statement is:
Satisfaction:
I get as much satisfaction out of things as I used to (0)
I don’t enjoy things the way I used to (1)
I don’t get real satisfaction out of anything anymore (2)
I am dissatisfied and bored with everything (3)
Biological: genetic (Oruc et al.) Aim
Believed depression has a genetic basis and looked at the link between bipolar and first relatives. First degree relatives share 50% of DNA.
Oruc et al. procedure
A sample of 42 participants with a diagnosis of bipolar disorder were drawn from two psychiatric hospitals in Croatia. Control group of 40 ppts also included.
Information collected from ppts and family members alongside medical records.
Sixteen of the bipolar group had at least one first relative diagnosed with a major affective disorder.
DNA testing was conducted to test for polymorphisms in serotonin receptor 2c (5-HTR2c) and the serotonin transported (5-HTT) genes.
Oruc et al. findings
There were no significant associations in the sample. Polymorphisms in these genes could be responsible for an increased risk of developing bipolar disorder in females.
Biological (Neurochemical) - Schildkraut
Schildkraut (1965) suggested too much noradrenaline causes mania and too little causes depression. Serotonin was also found to exist in low levels for both depression and mania. Both serotonin and noradrenaline imbalances are involved in affective disorders.
Cognitive (Beck)
Depression is due to faulty processing of information resulting in cognitive distortion.
Beck developed the cognitive triad (negative views about the world - obstacles blocking happiness, about oneself - worthless and not capable of being happy, about the future - anticipation of failure or rejection) these are a constant loop in the sufferers mind.
Negative views form a reality for that person leading to them spiraling into lower moods.
Cognitive distortion: distortion of thoughts automatic process which occurs as a result of earlier life processes, developed through schemas.
Learned helplessness/attributional style (Seligman) aim
Seligman investigated how well attributional style could predict depressive symptoms.
Seligman procedure
51 patients with bipolar or unipolar from the same outpatient clinic participated in the study during a depressive episode. They were compared to a 10 ppt control group.
First they completed the BDI and then the Attributional Style Questionnaire consisting of 12 hypothetical good and bad events. The participants made attributions for each one and rated each on a seven-point scale for internality, stability and globality.
Seligman findings
The bipolar and unipolar participants had more pessimistic, negative attributional styles then the control group. The more severe the BDI score the worse the pessimism on the ASQ.
Biological: chemical/drugs: MAO
MAOIs inhibit the work of the enzyme monoamine oxidase which is responsible for breaking down/removing neurotransmitters like norepinephrine, serotonin and dopamine. MAOIs prevent them from being broken down allowing them to remain at high levels in the brain.
They have numerous side effects and may cause issues with withdrawal.
Biological: chemical/drugs: SSRIs
SSRIs, such as Prozac are a newer antidepressant that stops serotonin being reabsorbed and broken down allowing it to remain at higher levels in the brain. They are the most prescribed and have less side effects.
Electro-convulsive Therapy
ECT is a procedure done under general anaesthesia.
The treatment involves passing electricity through the brain to induce a brief seizure.
Patients undergo a course of ECT ranging from 6-12 sessions, often being given twice a week or at longer intervals to prevent relapse.
It is applied to the non-dominant hemisphere to reduce memory loss.
Rarely used as there is little evidence that it is more effective than other forms of therapy.
Cognitive Restructuring (Beck)
Talking therapy - one-to-one interaction between patient and therapist. Focuses on identifying and questioning illogical thinking.
- Explain theory of depression to help understand way of thinking
- Observe and record thoughts to identify irrational beliefs
3.Challenge negative thoughts and replace with positive thoughts - Completes once patient can restructure thoughts or once there is reduction in depressive symptoms
Rational Emotive Behavioural Therapy (Ellis)
Based on stoicism (affected by their own perception). A person is depressed as a result of their perceptions towards things. Focuses on the ABC model:
A: Activating event
B: Belief about A
C: Consequences of B
REBT procedure
Ellis believes the most important aspect is the beliefs as negative beliefs lead to depression.
The goal is to help individuals create and maintain rational patterns of thinking. This means changing thoughts which lead to negative behaviour.
A REBT therapist forcefully questions irrational beliefs to try to reformulate them. This enables the patient to recognise that they choose how to think and feel about setbacks. Ellis then expanded the ABC model to include:
D: disputing the irrational beliefs
E: the effect of successful disruption of the irrational beliefs
Ellis support
Researchers looking into effectiveness found group given REBT had significant improvements over the baseline and control groups
Impulse Control Disorder Definition
An impulse control disorder where the person feels a compulsion to carry out a certain behaviour, rather than take a substance (e.g., alcohol, food, cigarettes, etc.). Types of behaviours could include gambling, stealing and pyromania.
Definitions (Griffiths)
All addictions have a number of common characteristics including:
salience: activity takes over as most important thing in their life
mood modification: experience creates a buzz
tolerance: increasing amounts needed to fulfil
withdrawal: unpleasant feelings when stopped
conflict: between them and others
relapse: return to addiction years after controlling