Abnormal A&P Flashcards

1
Q

What is a cleft

A

-an abnormal opening (fissure) in an anatomical structure that is typically closed

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2
Q

If there is a failure of parts to fuse at midline what is it called

A

a cleft

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3
Q

What is present if all structures are present but not fused or developed normally

A

a cleft

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4
Q

what are causes of a cleft

A
  • embryologic under development
  • chromosomal disorders
  • genetic disorders
  • maternal factors
  • environmental teratogens
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5
Q

what are examples of embryologic under development

A

cell migration delay and cell disruption

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6
Q

what are examples of maternal factors that can cause a cleft

A
  • older age
  • utero factors
  • maternal malnutrition
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7
Q

what are examples of environmental teratogens that can cause a cleft

A
  • cigarette smoke
  • dilantin
  • thalidomide
  • valium
  • lead
  • corticosteroids
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8
Q

What are the different classification of clefts

A
  • normal
  • complete
  • incomplete
  • unilateral
  • bilateral
  • soft palate cleft
  • hard palate cleft
  • complete palate cleft
  • bilateral palate cleft
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9
Q

What does a cleft of the primary palate include

A

lip and alveolus

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10
Q

what are the different types of primary palate clefts

A
  • complete (thru to incisive foramen) or incomplete (lip only)
  • unilateral or bilateral
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11
Q

what does a cleft of the secondary palate include

A

hard palate and velum

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12
Q

what are the different types of secondary palate clefts

A
  • complete (uvula to incisive foramen) or incomplete (bifid uvula into velum)
  • with or without cleft lip
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13
Q

What are the types of sub mucous cleft palates

A

Overt and occult

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14
Q

describe the overt sub mucous cleft palate

A
  • Identified thru intraoral exam
  • bifid uvula
  • zona pellucida (blush area in middle of velum; V at rest)
  • posterior hard palate notch
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15
Q

describe the occult sub mucous cleft palate

A
  • hidden on nasal surface

- via nasoendoscopy

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16
Q

what are the different types of facial clefts

A
  • oblique

- midline (median)

17
Q

describe oblique facial clefts

A
  • unilateral or bilateral
  • affects skeletal and soft tissue
  • begins at mouth> lateral, horizontal, upward (extreme disfigurement)
18
Q

describe midline facial clefts

A
  • mild
  • causes cranial base anomalies
  • associated with other midline anomalies
19
Q

what are examples that cause cranial base anomalies in midline facial clefts

A
  • encephalocele

- absent corpus callosum

20
Q

what are examples that are associated with other midline anomalies in midline facial clefts

A
  • bifid nose
  • frontonasal dysplasia
  • hypertelorism
  • holoprosencephaly