Aaron: Hematology Flashcards

1
Q

Polycythemia will have a high or low EPO level?

A

Low EPO

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2
Q

Elevated Carboxyhemoglobin, elevated hemoglobin, could mean what?

A

Carbon Monoxide poisoning

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3
Q

High Hemoglobin, normal EPO, and itching after a hot shower means what?

A

PCV, look at Jak2 mutation

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4
Q

Elevated Hemoglobin, elevated EPO, normal carboxyhemoglobin, negative urinalysis, what should be the next test?

A

Nocturnal Oximetry, look for OSA, could cause elevated hemoglobin

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5
Q

Heparin Induced Thrombocytopenia (HIT) has two types, which is the most common one?

A

Type 2

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6
Q

Type 1 HIT usually arises within 2 days of heparin exposure, what is the low platelet value? What is Type 1 HIT?

A

100,000 platelets, non-immune mediated platelet clumping, resolves several days after medication is d/c

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7
Q

Warfarin reversal is done in what time frame?

Less than 10 minutes?
12-24 hours?

A

10 minutes: Prothrombin Complex Concentrate

12-24 hours: Vitamin K

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8
Q

A patient has multiple blood transfusions, a new type and cross reveals no blood match compatibilities, why is this the case?

A

Alloantibodies

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9
Q

With the presence of CLL, what is the poorest prognostic factor?

A

Thrombocytopenia

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10
Q

If I am diagnosed with Multiple Myeloma, what is the test to evaluate systemic spread?

A

Whole body low dose CT scan

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11
Q

Erythroid Hyperplasia
RBC destruction
Ineffective Hematopoiesis

These three things affect what?

A

Iron Metabolism

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12
Q

Pernicious anemia will have what kind of pathological sampling?

A

Glandular Atrophy, Intestinal Metaplasia, and inflammation

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13
Q

Doxorubicin can cause cardiotoxicity, what is the test of choice to monitor this problem?

A

Radionuclide Ventriculography, if EF decreases by 10% stop the medication

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14
Q

What is another name for Leucovorin?

A

Folinic Acid

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15
Q

What drugs improve Anemia of Chronic Disease in RA patients?

A

Infliximab

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16
Q

Methotrexate can cause macrocytic anemia, what is lacking B9 or B12?

A

B9

17
Q

TTP has what enzyme deficiency?

What is the first treatment step?

A

ADAMS13 deficiency (bad metalloproteinase)

Plasma Exchange, first problem

18
Q

Prostate
Small Lung
Hodgkin Lymphoma

Osteolytic or Osteoblastic lesions?

A

Osteoblastic Lesions

19
Q

Myeloma
Non-small Lung
Non-Hodgkin Lymphoma

Osteolytic or Osteoblastic lesions?

A

Osteolytic Lesions

20
Q

Breast Cancer

Osteolytic or Osteoblastic lesions?

A

Both

21
Q

When sorting out Normocytic anemia, what is the first lab test that should be ordered?

A

Reticulocyte Count

22
Q

Most common brain tumor cause?

A

Metastatic Cancer

23
Q

When Lung Cancer spreads to Supraclavicular lymph nodes and brain, where should the biopsy be taken from?

A

Supraclavicular lymph nodes, easier access and safer

24
Q

Most common IVC filter complication, long term?

A

Recurrent DVTs, the filter does not fix the underlying problem

25
Q

What is the best eye melanoma treatment?

A

Radiation therapy

26
Q

EBV Mono usually enlarges the anterior or posterior lymph nodes?

If the lymph nodes are enlarged for 8+ weeks, what should be done?

A

Posterior Lymph Nodes

Lymph node biopsy

27
Q

Uremic patient, increased bleeding, what is the treatment?

A

Desmopressin, increased vWF, helps platelet function, binding platelets

28
Q

Cryoprecipitate is used for what and contains what?

A

Contains fibrinogen, factors 8 and 12, and vWF, helps life threatening bleeding problems 2/2 coagulation problems usually 2/2 platelet dysfunction

29
Q

What am I?

Primary Hyperparathyroidism
Endopancreatic Tumors
Pituitary Tumors

A

MEN 1

30
Q

What am I?

Medullary Thyroid Cancer
Pheochromocytoma
Parathyroid Hyperplasia

A

MEN 2a

31
Q

What am I?

Medullary Thyroid Cancer
Pheochromocytoma
Neuromas or Marfans

A

MEN 2b

32
Q

Thyroid biopsies should be done for what size tumor?

A

Greater than 1 cm