A1 Blockers

Question 1

Block A1 receptors in arterioles and venules and produce less reflex tachycardia than non selective A antagonists such as phentolamine.

Answer 1

Prazosin, terazosin, and doxazosin

Question 2

Bp is reduced more in the upright position than in supine. Retention of salt and water occurs when used alone and is more effective with the use of B blockers and diuretics.

Answer 2

A1 blockers

Question 3

Used primarily in men with concurrent hypertension and BPH

Answer 3

A1 blockers

Question 4

Extensively metabolized but undergoes little first pass metabolism

Answer 4

Terazosin

Question 5

Some patients develop positive test for antinuclear factor but is not associated with rheumatic symptoms

Answer 5

Prazosin

Question 6

Not adversely and may even beneficially affect plasma lipid profile

Answer 6

A1 blockers

Question 7

Nonselective agents that are useful in diagnosis and treatment of pheochromocytoma and in other clinical situations associated with exaggerated release of catecholamines

Answer 7

Phentolamine and phenoxybenzamine