A04 Brainstem Nuclei and Cranial Nerves Flashcards
List the components of the brainstem.
1 - Medulla oblongata.
2 - Pons.
3 - Midbrain.
Through which structure does the brainstem join the spinal cord?
The foramen magnum.
Which structures enable communication with the cerebellum?
Where are these structures located?
- The superior, middle and inferior cerebral peduncles.
- They are located on the dorsal surface of the brainstem.
What do the cerebral peduncles contain?
The portion of the ascending and descending nerve tracts that pass between the cerebrum and pons.
What is the crus cerebri?
The anterior portion of the cerebral peduncles which primarily (but not exclusively) contains motor tracts.
List 4 discrete grey areas within the brainstem.
1 - Cranial nerve nuclei.
2 - Reticular formation.
3 - Olivary nuclei.
4 - Cuneate nuclei.
5 - Gracile nuclei.
What is the reticular formation?
Describe its course in the CNS.
A network of neurones that extends from:
1 - The spinal cord.
2 - To the dorsal brain stem.
3 - To the tegmentum of the midbrain.
4 - Terminating in the thalamus.
What is the function of the reticular formation?
List 7 structures with which the reticular formation synapses in order to carry out its function.
- The reticular formation has some control over which sensory signals reach the cerebrum and come to our conscious attention.
- It is able to do this by synapsing with:
1 - The spinoreticular tract.
2 - The spinothalamic tracts.
3 - The medial lemniscus.
4 - Cranial nerve nuclei.
5 - The cerebellum.
6 - Subthalamic, hypothalamic and thalamic nuclei.
7 - Both the primary motor and sensory cortices of the cerebral cortex.
List the components of the descending tracts that are influenced by the reticular formation.
1 - Reticulobulbar tracts (parasympathetic outflow).
2 - Reticulospinal tracts (parasympathetic outflow).
3 - The corpus striatum.
4 - The cerebellum.
5 - The red nucleus.
6 - The substantia nigra.
7 - The tectum.
8 - Nuclei of the diencephalon.
Give an example of an adaptation of the reticular formation.
The neurones have unusually long dendrites which maximise their ability to receive and integrate synaptic outputs from most of the fibres that extend through the brainstem.
What is the medial lemniscus?
A large ascending bundle of heavily myelinated axons formed by the internal arcuate fibres that decussate in the medulla oblongata.
What is the red nucleus?
What gives the red nucleus its colour?
- A nucleus in the rostral midbrain that is involved in motor coordination.
- The colour is due to the presence of iron in haemoglobin and ferritin.
What is the substantia nigra?
One of the 6 nuclei composing the basal ganglia.
List the nuclei composing the basal ganglia.
1 - Substantia nigra.
2 - Caudate nucleus.
3 - Lentiform nucleus.
4 - Amygdala.
5 - Claustrum.
6 - Subthalamic nucleus.
What is the corpus striatum?
The collective name given to the caudate nucleus and lentiform nucleus of the basal ganglia.
List 3 influences of the reticular formation on the control of skeletal muscle.
1 - The reticular formation modulates muscle tone and reflex activity via the reticulospinal and reticulobulbar tracts.
2 - The reticular formation is involved in reciprocal inhibition (when flexors contract, antagonist muscles must relax).
3 - The reticular formation and vestibulospinal tract are together responsible for maintaining the tone of antigravity muscles when standing.
List the structures through which the reticular formation exerts an influence on the autonomic nervous system.
1 - Reticulospinal tracts.
2 - Reticulobulbar tracts.
*These are descending tracts which descend to sympathetic and parasympathetic outflow.
How does the reticular formation exert an influence on the endocrine system?
By directly and indirectly influencing hypothalamic nuclei, which controls the secretions of the pituitary gland.
Describe the reticular activating system.
- Ascending pathways project information to the reticular formation.
- The reticular formation integrates the information and, if appropriate, will arouse an individual to a more alert state (for example waking up from sleep).
How does the reticular formation influence vital centres?
- Cardiovascular and respiratory centres are located within the reticular formation.
- Via the hypothalamus and nuclei involved in autonomic outflow, stimulation of these centres can:
1 - Influence respiratory rhythm.
2 - Slow heart rate.
3 - Reduce systemic blood pressure.
Which structures in the brainstem are the ventral horn and dorsal horn of the spinal cord analogous to?
- The motor fibres of the cranial nerves arise from neuronal cell bodies that lie deep within the brainstem. These motor nuclei are analogous to the ventral horn of the spinal cord.
- The sensory fibres of the cranial nerves arise from neuronal cell bodies in the superficial brainstem. These sensory nuclei are analogous to the dorsal horn of the spinal cord.
List the cranial nerves that are involved in special sensory input.
Cranial nerves 1, 2 and 8.
List the cranial nerves that are involved in the control of eye movement and pupillary constriction.
Cranial nerves 3, 4 and 6.
List the cranial nerves that are involved in motor output only.
Cranial nerves 11 and 12.
List the cranial nerves that are involved in mixed motor and sensory functions.
Cranial nerves 5, 7, 9 and 10.
List the cranial nerves that have parasympathetic functions.
Cranial nerves 3, 7, 9 and 10.
Which cranial nerves are distributed entirely in the head and neck?
All but the vagus nerve.
Which cranial nerves have nuclei in the brainstem?
All but the olfactory and optic nuclei.
List the cranial nerves.
1 - Olfactory.
2 - Optic.
3 - Oculomotor.
4 - Trochlear.
5 - Trigeminal.
- Ophthalmic.
- Maxillary.
- Mandibular.
6 - Abducens.
7 - Facial nerve.
8 - Vestibulocochlear nerve.
9 - Glossopharyngeal.
10 - Vagus.
11 - Accessory.
12 - Hypoglossal.
List the types of nerve fibres that convey information between the brainstem and the functional components of the cranial nerves.
Afferents:
1 - Special somatic afferents (SSA).
2 - General somatic afferents (GSA).
3 - Special visceral afferents (SVA).
4 - General visceral afferents (GVA).
Efferents:
5 - General somatic efferents (GSE).
6 - Special visceral efferents (SVE).
7 - General visceral efferents (GVE).
*Some of these fibres are also present in spinal nerves.
What is the function of special somatic afferents?
To transmit special senses such as sight, hearing and balance.
What is the function of general somatic afferents?
- To transmit sensation from the skin and mucous membranes.
- Sensations involved include pain, temperature, touch and proprioception.