A: Mediastinum notes Flashcards

1
Q

Subdivisions of mediastinum

A
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2
Q

Contents of superior mediastinum

A

Spread of cancer from mediastinal lymph nodes can include:
- Nerves: R/L vagus, L recurrent laryngeal branch of L vagus, R/L phrenic nerves
- Arteries: aortic arch + branches (brachiocephalic, L subclavian, L common carotid)
- Veins: R/L brachiocephalic, SVC, arch of azygos vein
- Thymus gland
- Trachea, oesophagus (viscera)
- Thoracic duct
(NAV TTT)

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3
Q

Contents of posterior mediastinum

A

Spread of cancer from mediastinal lymph nodes can include:
- Descending aorta, thoracic aorta + branches
- Azygos and hemiazygos veins
- Thoracic duct and associated lymph nodes
- oEsophagus
- Sympathetic trunks + associated nerves
- vagus nerves

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4
Q

Contents of anterior mediastinum

A
  • Thymus gland
  • Fat
  • Lymph nodes
  • Sternopericardial ligaments (sternum to pericardium)
  • Connective tissue
    (T/F, L S C)
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5
Q

Which vein is more prone to injury in children and why?

A

Left brachiocephalic vein because it rises above the upper border of manubrium in childdren

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6
Q

Where do the brachiocephalic veins form?

A

Behind medial ends of clavicles at junction of internal jugular vein + subclavian vein

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7
Q

Where do the brachiocephalic veins join?

A

Behind lower edge of first right costal cartilage to form the SVC

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8
Q

Which vein does the SVC receive immediately before it enters the pericardial sac?

A

Azygos vein

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9
Q

Explain the course of azygos vein

A
  • Arises at L1 or L2 by junction of veins (communicate with IVC)
  • Passes through adductor hiatus –> enters posterior mediastinum
  • Continues upwards on the right side of the thoracic vertebrae bodies
  • Receives posterior intercostal veins
  • Forms an arch over the root of right lung –> enters posterior SVC immediately before it enters the pericardial sac
  • Drains mediastinum and the posterior thoracic + abdominal walls on the right
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10
Q

Explain the course of hemiazygos vein

A
  • Arises at abdomen by junction of veins (communicate with IVC)
  • Passes through adductor hiatus –> enters posterior mediastinum
  • Continues upwards on the left side of the thoracic vertebrae bodies
  • Receives posterior intercostal veins
  • Crosses to the right side (posterior to thoracic aorta) to enter azygos vein
  • Drains mediastinum and the lower posterior thoracic + abdominal walls on the left
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11
Q

What does the accessory hemiazygos vein drain?

A

Mediastinum and upper posterior thoracic wall on left

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12
Q

What does the azygos system anastomose?

A

IVC and SVC if IVC is blocked

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13
Q

Where does the aorta arise?

A

Left ventricle, posterior to origin of pulmonary artery

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14
Q

Where is the ascending aorta and what are its branches?

A

Behind the sternum
Branches = right and left coronary arteries

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15
Q

Explain the course of aortic arch and its branches

A

Course:
- Begins at level of sternal angle, arches posteriorly and to the left.
- Initially anterior to trachea, but later lies lateral to trachea and oesophagus
- Continues as descending aorta at T4/T5 junction

Branches:
- Brachiocephalic trunk (divides into right subclavian and common carotid arteries behind right sternoclavicular joint)
- Left common carotid artery
- Left subclavian artery (passes between anterior and middle scalene to enter axilla)

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16
Q

Explain the course of the descending aorta and its branches?

A

Course:
- Begins at T4/T5 junction
- Descends through posterior mediastinum (left of upper thoracic vertebrae and anterior to lower thoracic vertebrae)
- Passes through adductor hiatus of the diaphragm at T12 to enter the abdomen

Branches:
- Posterior intercostal arteries supply intercostal spaces and thoracic wall: 9 pairs (first 2 spaces supplied by subclavian artery)
- Right and left bronchial arteries to bronchi and lung tissue
- Oesophageal branches to oesophagus

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17
Q

Patent ductus arteriosus

A

Congenital heart defect where ductus arteriosus fails to close at birth. Oxygenated + deoxygenated blood mix.

18
Q

What type of innervation do the vagus nerves provide?

A
  • Parasympathetic innervation to the thoracic viscera
  • They carry sensory fibers from thoracic viscera about normal physiology processes and reflex processes
  • Do NOT carry pain sensation
19
Q

Explain the course of right vagus nerve

A

Descends to the right of trachea –> posterior to root of the lung –> oesophagus

20
Q

Explain the course of left vagus nerve

A

Descends between left common carotid and left subclavian arteries –> crosses left side of aortic arch –> posterior to root of the lung –> oesophagus

21
Q

How do the vagus nerves enter the abdomen?

A

Through oesophageal opening in the diaphragm

22
Q

Where do the vagus nerves pass to enter the superior mediastinum?

A

Posterior to brachiocephalic veins

23
Q

Explain course of left recurrent laryngeal nerve

A

Arises from the left vagus nerve close to the aortic arch and loops under it

24
Q

Explain course of right recurrent laryngeal nerve

A

Loos around the right subclavian artery in the root of the neck

25
Q

Where do the recurrent laryngeal nerves ascend?

A

In the groove between trachea and oesophagus to reach the larynx

26
Q

What disease is more likely to involve the left recurrent laryngeal nerve rather than the right and what are the consequences?

A

Diseases of the thorax (such as enlarged lymph nodes associated with lung cancer) –> paralysis of left vocal cord only –> hoarseness of the voice

27
Q

What disease is more likely to involve the right recurrent laryngeal nerve rather than the left and what are the consequences?

A

Cancer of the apex of the right lung –> paralysis of right vocal cord only –> hoarseness of the voice

28
Q

Explain course of phrenic nerves

A
  • Arise from cervical plexus (C3-5)
  • Enter superior mediastinum
  • Right phrenic nerve descends on the right of SVC
  • Left phrenic nerve descends on the left of aortic arch
  • Entering middle pericardium, each phrenic nerve descends within the pericardial sac (anterior to the root of the lung) –> diaphragm
  • Trick: PHrenic nerve in Front of root of lung
29
Q

Explain innervation of phrenic nerves

A
  • Motor innervation to diaphragm
  • Sensory innervation to central aspects of: diaphragm, fibrous pericardium and parietal layer of serous pericardium
30
Q

What system are the sympathetic trunks a part of?

A

Autonomic nervous system (ANS)

31
Q

What connects the trunks to the thoracic spinal nerves?

A

White and gray rami communicans

32
Q

What is sympathectomy?

A

Division of sympathetic trunks to reduce blood pressure in severe cases of hypertension by preventing vasoconstriction and reducing peripheral resistance

33
Q

Branches of sympathetic trunks and what type of fibres/nerves they carry

A

Greater, lesser and least splanchnic nerves
They carry:
- Preganglionic sympathetic fibres from the thoracic ganglia to prevertebral ganglia of abdomen
- Visceral afferent nerves from the abdomen

34
Q

Explain course of thoracic duct

A
  • Lymphatic duct that begins as cysterna chyli in the abdomen
  • Passes through aortic opening in diaphragm to enter posterior mediastinum
  • Ascends on vertebral bodies, posterior to oesophagus, right of midline
  • moves to left of midline, ascends through superior mediastinum and enters neck
  • Drains into venous system at junction of left internal jugular and left subclavian veins
35
Q

What are the openings in the diaphragm?

A

T8 = Inferior vena cava in the central tendon (I8)
T10 = oesophageal hiatus for oEsophagus + vagus nerves (10 Eggs)
T12 = aortic hiatus for Aorta + Thoracic duct (At 12)

Mnemonic: I8 (I ate) 10 Eggs AT 12
I8 = Inferior vena cava
10 Eggs = (o)Esophagus (+ vagus nerves) (T10)
AT 12 = Aorta + Thoracic duct (T12)

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41
Q
A

Trick for neurovascular bundle: VAN (posterior inercostal Vein, Artery and Nerve from top to bottom)

42
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