A Level - Keywords Flashcards
cell signalling
how cells communicate with each other. Done with nervous impulses or hormones
Stimulus
change in an environment that causes a response
Response
change in behaviour/physiology as a results of a stimulus
Ectotherm
an organism that relies on external sources of heat to regulate body temperature
Endotherm
an organism that can control the generation or loss of heat to maintain its body temperature using physiological or behavioural responses
Homeostasis
the maintenance of the internal environment in a constant state despite external changes
Negative feedback
a process that brings about a reversal of any change in conditions in order to return to
an optimum steady state. Essential for homeostasis.
Positive feedback
a process that increases any change detected by the receptors. Does not lead to homeostasis
Generator potential
Small depolarisation caused by sodium ions entering the cell
Resting potential
when neurone is at rest (no stimulus), -70mV.
sodium/potassium ion pumps [3 out/2 in], K+ leakage
Depolarisation
loss of polarisation due to entry of Na+ entering the cell. Potential difference across membrane becomes less negative
Threshold potential
creates and action potential there is a big enough stimulus for enough Na+ enter the cell for the potential difference to exceed -50mV
Action potential
Membrane is depolarised to +40mV. All or nothing response. Transmitted along the axon membrane
Repolarisation
membrane becomes polarised again due to loss of K+ through v-g channels. Potential difference across membrane becomes more negative
Hyperpolarisation
too many K+ diffuse out - potential difference under -70mV
Refractory period
following an action potential, there is a need to redistribute sodium and potassium ions and restore resting potential. During this time another impulse cannot be generated. Ensures impulses separated, determines maximum frequency of impulse transmission, ensure impulse passes in one direction only along axon
Local currents
movements of ions along the neurone
Saltatory conduction
how the action potential ‘jumps’ from one Node of Ranvier to the next
Endocrine glands
produce and secrete hormones directly into the blood - they have no ducts.
Exocrine glands
do not produce hormones - they secrete molecules into a duct which carries them to where they are needed .
Hormone
molecules released by endocrine glands into the blood and act as messengers carrying a signal from the endrocrine gland to the target tissue.
Target cells/tissue
possess specific receptors on their cell surface membrane which is complementary in shape to a hormone molecule.
Neurotransmitter
a chemical that diffuses across the synaptic cleft to transmit a signal to the post- synaptic membrane
Cholinergic synapse
use acetylcholine as the neurotransmitter
Acetylcholinesterase
enzyme that breaks down acetylcholine in the synaptic cleft
Summation
how several small potential changes across the axon/dendron membrane can combine to produce one larger change in potential difference across the membrane
First messenger
hormones that transmits a signal around the body in the blood
Second messenger
cAMP which transmits a signal inside the cell
Hepatocytes
liver cells
Diabetes mellitus
a disease in which you can’t control your blood glucose concentrations effectively
Hyperglycemia
Blood glucose levels are too high
Hypoglycemia
blood glucose levels are too low
Glycogenolysis
glycogen being converted into glucose. Occurs in the liver.
Gluconeogenesis
fatty acids/amino acids –> glucose. Occurs in the liver.
Glycogenesis
glucose being converted into glycogen. Occurs in the liver.
Myogenic
muscle can initiate its own contractions
Excretion
removal of the unwanted / toxic / waste, products of metabolism
Deamination
Removes the amine group from amino acid - produces a keto acid (can be respired) and also produces ammonia (soluble and highly toxic). Occurs in the liver
Ornithine cycle
ammonia is converted into urea