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CP > A: CORONARY ARTERY DISEASE > Flashcards

A: CORONARY ARTERY DISEASE Flashcards

1
Q

A general term that refers to several diseases other than atherosclerosis

A

Coronary Artery Disease

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2
Q

heart disease with primary manifestations that result from myocardial ischemia owing to atherosclerotic CAD

A

Ischemic Heart Disease

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3
Q

An episodic, reversible oxygen insufficiency, is the most common form of IHD

A

Angina Pectoris

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4
Q

Chest discomfort that are attributable to insufficient myocardial oxygen

A

Angina Pectoris

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5
Q

Types of Angina

A

*Stable (Classic) Angina
*Unstable Angina
*Angina Decubitus
*Prinzmetal Angina

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6
Q

More predictable pattern

A

Stable (Classic) Angina

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7
Q

Stable (Classic) Angina is relieved by

A

Rest or Nitroglycerin

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8
Q

Pain has referred as SQUEEZING, GRIP LIKE SUFFOCATING

A

Stable (Classic) Angina

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9
Q

Lasts for minutes

A

Stable (Classic) Angina

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10
Q

Angina at rest

A

Unstable Angina

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11
Q

Decreased responded to NTG

A

Unstable Angina

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12
Q

Angina Decubitus is also known as

A

Nocturnal angina

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13
Q

Not specifically related to either rest or exertion

A

Angina Decubitus

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14
Q

Gravitational forces shifts fluid within body

A

Angina Decubitus

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15
Q

Angina Decubitus drugs reduce left ventricular volume

A

Diuretics alone or in combination

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16
Q

Angina Decubitus: Nitroglycerin may relieve

A

Paroxysmal nocturnal dyspnea (PND)

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17
Q

Occurs at rest

A

Prinzmetal Angina

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18
Q

What drugs are used for the treatment of Prinzmetal Angina

A

Calcium Channel Blocker and Beta blockers

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19
Q

In this type of Angina, the Nitroglycerin doesn’t provide relief

A

Prinzmetal Angina

20
Q

Bind bile acids within the intestines and prevent from being reabsorbed

A

Bile Acid Binding Resins

21
Q

Drugs of Bile Acid Binding Resins

A
  1. Cholestyramine
  2. Colestipol
  3. Colesevelam
22
Q

Inhibit the enzyme HMG-CoA, resulting in reduction of cholesterol

A

Statins or HMG COA Inhibitor

23
Q

Drugs of Statins or HMG COA Inhibitor

A

*Atorvastatin
*Fluvastatin
*Lovastatin
*Pitavastatin
*Pravastatin
*Rosuvastatin
*Simvastatin

24
Q

Inhibits cholesterol synthesis and lower LDL and bile acids

A

Fibric Acid Derivatives

25
Q

Precautions in Fibric Acid Derivatives

A
  • GI effects
  • Affects Liver function test
26
Q

Drugs of Fibric Acid Derivatives

A

Fenofibrate and Gemfibrozil

27
Q

Lowering of LDL and triglycerides

A

Niacinamide

28
Q

Respiration of oxidation - reduction reactions

A

Niacinamide

29
Q

Indication of Niacinamide

A

Elevated total cholesterol and low LDL

30
Q

Special Precautions in Niacinamide

A
  • GI effects
  • Itchy skin
  • Cases of severe liver toxicity
31
Q

Inhibits the intestinal absorption of cholesterol and related phytosterols

32
Q

Indication of Ezetimibe

A
  • Adjunctive therapy along with dietary measures
  • Used in combination with STATINS
33
Q

Venous dilation

34
Q

Indication of Nitrates

A

Acute attacks of angina pectoris

35
Q

Associated with long term use of nitrates

A

Nitrate Tolerance

36
Q

Reduction of oxygen demand

A

Beta Blocker

37
Q

Safety Precautions in Beta Blocker

A
  • Should be avoided in Prinzmetal angina
  • Asthma is a relative contraindication
  • Hypoglycemia
38
Q

All beta blockers are likely to be equally effective for

A

Stable angina

39
Q

Reverse coronary spasm by inhibiting calcium influx

A

Calcium Channel Blockers

40
Q

Decrease coronary vascular resistance

A

Calcium Channel Blockers

41
Q

Used in stable angina that is not controlled by nitrates and beta blockers and in patients for whom beta blocker therapy is not advisable

A

Calcium Channel Blockers

42
Q

Drugs of Calcium Channel Blocker

A

Verapamil
Diltiazem
Nifedipine

43
Q

Inhibits platelet aggregation induced by adenosine diphosphate

A

Ticlopidine

44
Q

Just like ticlopidine but produces anti thrombotic effect

A

Clopidogrel

45
Q

Drugs of Antiplatelet Agents

A

Aspirin
Ticlopidine
Clopidogrel

46
Q

Recommended for clinically diagnosed hypertensive agents who are experiencing angina

A

ACE & ARBs

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