9.2 PRACTICE QUESTIONS Flashcards
Name the type of blood vessel which is most likely to become obstructed by fatty deposits, leading to heart disease. (1 mark)
Artery
Put the series of events leading to a heart attack in order. (2 marks)
E C B A D
Name the chemical substance that is the principle cause of the fatty deposits that build up in the lead-up to heart disease. (1 mark)
Cholesterol
Identify the object in Figure 1 below and explain its use in treating heart disease. (2 marks)
Stent
Keeps the arteries open by increasing the diameter of the lumen
Name the group of drugs prescribed to patients at high risk of heart disease to reduce their cholesterol levels. (1 mark)
Statins
CHD is a major cause of death worldwide.
Describe how CHD develops and the main causes. (4 marks)
-Fatty deposits build up in coronary arteries
-Causing the lumen to narrow over time
-Leading to reduced blood flow to the heart muscle
-High levels of cholesterol
CHD is classed as a non-communicable disease.
Suggest what is meant by a non-communicable disease. (1 mark)
A disease that is not transmissible directly from one person to another.
Scientists monitored the effect of five of these drugs on one person for over 10 years, the results are shown in Figure 1 below.
Compare the effectiveness of the treatments in reducing the risk of CHD. (4 marks)
-Neither A or B is effective because HDL levels dropped
-A+B together is effective because HDL levels went up
-C+D together is not effective because HDL levels dropped
-D alone is the most effective treatment
-C alone is unkown from data given
Statins are a commonly prescribed drug which can reduce an individual’s risk of developing CHD.
Discuss the use of statins to prevent CHD. (4 marks)
Positives
-Statins decrease levels of LDL (‘bad’ cholesterol)
-reduced cholesterol levels leads to reduced rate of fatty deposits
Negatives
-Has to be remembered to be taken regularly, long term, in order to stay effective
-Statins can have side effects like muscle and kidney problems
Figure 1 shows the difference between a normal heart valve and a diseased heart valve when open and closed.
Explain why a severely diseased heart valve can cause problems and how it can be corrected. (6 marks)
Problems:
-Restricts bloodflow
-Blood flows in both directions instead of just forward
-Does not close properly, becomes leaky
-Prevents blood from circulating effectively
Corrections:
-Replace the valve
-With either a biological valve (human/pig) or mechanical valve (man-made)