9. Adaptive immunity and vaccines Flashcards
Third line of defence
Adaptive response
adaptive and contains immunological memory
Lymphatic system
networks of vessels and organs around the body that transport immune cells, pathogens and antigens- this is seperate to the circulartory system
Naive B cells
special lymphagoctyes that can be activated and divided into plasma and B memory cells
Plasma cells
specialised cells that make antibodies against a specific pathogen
B memory cells
specialised cells that remain in the body for a long time and can divide into plasma cells
Antibodies
proteins that can attach to specific antigen or pathogen and help destroy it
Phagoctyes
cells that can present antigens to the naive B cells to help activate them
How do b cells know what antibodies to produce?
humeral response only happens when bacteria, viruses and toxins are out of their host
B cells are produced and mature in the bone marrow
b cells have a specific receptor which can bind them to a certain antigen
Humeral response
antigen binds to a b cell with complementary receptor
stimulates B cell to divide into a lot of plasma and b memory cells
plasma cells make antibodies for specific antigen
b memory cells remain in the lymphatic system -> immunological memory
How to antibodies destroy pathogens?
designed to attach to specific pathogens
one antibody can attach to two antigens
speeds up phagocytosis
immunological memory
when encountering the antigen in the future the response is faster
cell mediated response
only works against foreign eukaryotic cells eg cancer, viral infected cells, transplant tissue
T cells are produced in bone marrow
T c cells target pathogen by making it go through apoptosis