7. Pathogens and Antibodies Flashcards
Definition of pathogens
are disease causing and infectious agents
includes bacteria, viruses, worms, fungi, protozoan parasite, prions
“germ theory” currently the recognised scientific theory for many diseases
What is a culture?
micro-organisms, tissue, tissue cells or other living matter grown in a specially prepared nutrient medium eg. cell growth= a culture of bacteria
Antigens
substances that interact with the immune system and the body to recognise pathogens present
proteins on pathogen’s surface or the toxins they produce may act as antigens
Immune system
mammalian system that defends an organism against disease and other foreign tissue
Levels of Defence
1st =barriers (innate response- non specific
2nd= chemical and general cellular defence (innate response)
3rd= humoral and cell-meditated responses
Bacteria
prokaryotic, unicellular organisms
can infect almost any type of body
bacteria replicates via binary fusion and multiply quickly
eg. mengitis, tetanus, strep throat
viruses
non-cellular pathogens
composed of genetic material (DNA and RNA) inside a protein coat
viruses cannot independently reproduce instead they insert their genetic material into host’s cell and use cell to replicate
eg. COVID-19 / rabies / AIDs
Protozoa
unicellular eukaryotic organisms
can be free-living or parasitic
eg. malaria / sleeping sickness
Prions
prions can be infectious proteins that destroy nerve cells in the brain
scrapie/ mad cow disease
Fungi
eukaryotic organisms
have ling branching filaments called huphae
generally diseases caused by fungi are not life threatening
eg. thrush, ringworm, athlete’s foot
Worms
multicellular eukaryotic organisms
parasites develop from an egg to larvae to an adult
develop slowly diseases caused= slow and chronic
eg. tapeworm-> malnutrition
methods of transmission
direct through skin contact, bodily fluids, airborne particles, contact with faeces, touching a surface
immune system lines of defence
inate/ non-specific ( first and second line of defence)
adaptive/ specific (third line of defence)