9-6 Overview of Adaptive Immunity Flashcards
1
Q
Adaptive immunity requires ____ and ____ of lymphocytes
A
expansion and differentiation
2
Q
Humoral immunity mediated by ____
A
antibodies produced by B cells
3
Q
Cell-mediated immunity mediated by ____
A
T cells
4
Q
Effector cells of B lymphocytes
A
antibody secreting plasma cells
5
Q
Effector cells of CD4 T lymphocytes
A
cytokines
6
Q
Effector cells of CD8
A
cytotoxic T lymphocytes
7
Q
B cell receptor recognizes…
A
Whole host of antigenic determinants: macromolecules, small chemicals
8
Q
T cell receptor recognizes…
A
Very small peptides
9
Q
Function of IgG
A
- microbe/toxin neutralization
- opsonization
- activation of complement
- antibody-dependent NK toxicity
- neonatal immunity
10
Q
Function of IgM
A
- activation of complement
11
Q
Function of IgA
A
- mucosal immunity
12
Q
Function of IgE
A
- helminth defense
- mast cell degranulation (allergies)
13
Q
MHC 1
A
- major histocompatibility complex molecule
- found on all healthy nucleated cells in body
- recognized by CD8 cytotoxic T cells
14
Q
MHC 2
A
- found on specialized, professional antigen presenting cells (macrophages, dendritic cells, B cells)
- recognized by CD4 T cells
