9 Flashcards
Which disorder causes neonates to demonstrate the presence of Bart’s hemoglobin that changes to beta-chain tetramers is adults?
Hemoglobin H disease
What common agars will Pasteurella sp. grow on?
SBA and chocolate agar
What is the anion gap formula?
anion gap = sodium - (chloride + bicarbonate)
What is the LDL formula?
LDL = total cholesterol - [HDL + (triglycerides/5)]
What is contact dermatitis mediated by?
T lymphocytes
What are the two general categories of nucleic acid amplification (NAA) techniques?
target amplification and signal amplification
What three factors contribute to Staph. aureus pathogenicity?
exfoliative and enterotoxins; natural colonization/resevoir; hyaluronidase
A decrease in what kind of cells in and AIDS patient results in an increase in susceptibility to infection?
CD 4+ cells
What lipid test is least affected by a patient’s fasting status?
cholesterol
Anti-factor VII inhibitor may cause what kind of hemophilia?
acquired hemophilia A
Which RBC parameter is not decreased in beta-thalassemia major?
RDW
What is the preferred solution for general disinfection of work surfaces in the lab?
10% sodium hypochlorite
What is the formula for absolute cell count?
abs. count = total count x % of cells counted
What is the formula for creatinine clearance?
creatinine clearance (mL/min) = (urine creat./serum creat.) x [urine vol. in mL/(time in hrs. x 60)]
What is the purpose of adventitial cells?
provide support for developing hematopoietic cells
What percentage of adipose cells make up the volume of bone marrow in the average adult?
approximately 50%
What kind of immunochemical electrophoresis uses antisera and quantitates an unknown antigen?
electroimmunoassay electrophoresis
Markedly increased 5-hydroxyindole acetic acid (5-HIAA) determination is presumptive evidence for what?
carcinoid tumor
Hepatocellular carcinoma, viral hepatitis, testicular tumors, and pancreatic cancer are all associated with increased levels of what?
AFP (alpha-fetoprotein)
What two tests can help confirm a suspected Cryptococcus sp.?
strong urease and phenoloxidase activity
What vitamin deficiency causes night blindness?
vitamin A
What vitamin deficiency causes beriberi?
thiamine
What vitamin deficiency causes rickets?
vitamin D
What vitamin deficiency causes scurvy?
vitamin C
What is the formula for a WBC count from a hemocytometer?
WBC count = (dilution factor x # cells counted x 10) / (# mm2 area counted)