8B- circadian rhythm sleep disorders Flashcards

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1
Q

circadian rhythm sleep disorders

A

a category of sleep disorders in which sleep is disrupted because the circadian rhythm and a person’s sleep wake schedule are misaligned

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2
Q

bright light therapy

A

a therapy to treat a sleep disorder in which the person is exposed to a bright light to reset the sleep wake cycle

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3
Q

delayed sleep phase syndrome

A

a circadian rhythm sleep disorder characterised by a delay in the timing of sleep onset and awakening compared with the timing that is desired

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4
Q

advanced sleep phase disorder

A

a circadian rhythm sleep disorder characterised by an advance in the timing of sleep onset and awakening compared to the timing that is desired

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5
Q

shift work

A

work that regularly takes place outside of normal business hours particularly at night and the very early morning, can cause a circadian rhythm sleep disorder

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6
Q

what is a circadian phase disorder?

A

Circadian phase disorder refers to sleep disorders that involve disruptions to a person’s sleep-wake cycle as there is a mismatch between a person’s normal sleep-wake pattern (reality) and the sleep-wake pattern that is required of them (expectation).

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7
Q

what can circadian rhythm disorders cause?

A

distress/dysfunction
excessive sleepiness/insomnia/ impairment in functioning
harder to function day to day

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8
Q

what are 3 circadian phase disorders?

A

advanced sleep phase disorder
delayed sleep phase syndrome
shift work

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9
Q

what can circadian rhythm sleep disorders be treated with?

A

bright light therapy which involves exposing a person to light for a specific amount of time to reset the sleep wake cycle. strategic exposure to light prompts the wake inducing biological mechanisms involving the circadian rhythm and suprachiasmatic nucleus and delays melatonin release, promoting wakefulness

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10
Q

what are some light sources for BLT

A

safe but artificial source from a specifically designed light box, desk lamp, floor lamp, visor hat with attached light or dawn simulator light
or may be natural sunlight if deemed reliable
ideal length and timing of light exposure is dependent on the type of disorder being treated

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11
Q

what is DSPS

A

delayed sleep phase syndrome is a sleep disorder characterised by a delay in timing of sleep onset and awakening compared to the desired timing
delay is usually 2 or more hours, with a person falling asleep later than required or conventionally accepted, causing a delay in awakening

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12
Q

what does the delay in sleep onset contribute to?

A

a sleep disorder when a person is unable to achieve the recommended amount of sleep because they have to wake up for work/school

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13
Q

how does DSPS occur

A

because the internal body clock doesn’t match the external cues like light and darkness. this delays sleep and wake times

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14
Q

give an example of DSPS

A

instead of sleeping at 10 and waking at 8, they may sleep at 1 and wake up at 11

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15
Q

when is DSPS seen throughout the lifespan

A

adolescent sleep-wake cycle shift

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16
Q

in order to be diagnosed what are the conditions?

A

must experience symptoms for more than 3 months
oftentimes, this also implies symptoms are not getting better, or are worsening.

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17
Q

what are some predisposing factors for DSPS?

A

age
longer than average circadian rhythm
delayed night time signal to the SCN, which delays melatonin release
less sensitive to morning light, would have a lack of light cues to the SCN to signal a reduction in melatonin release

18
Q

how can bright light therapy be used as a treatment for DSPS?

A

exposed to the bright light source in the morning at an appropriate awakening time.
external cue to the SCN, promoting wakefulness by sending signals to release cortisol
helps the SCN send signals for melatonin release at an earlier and more appropriate sleeping time, promoting sleep

19
Q

what is ASPD

A

advanced sleep phase disorder is a circadian rhythm sleep disorder characterised by an advance in the timing of sleep onset and awakening compared to the desired timing

20
Q

how does ASPD occur?

A

internal body clock is set earlier than normal, making them feel tired earlier in the evening and causing them to wake up earlier in the morning

21
Q

give an example of ASPD

A

instead of sleeping at 10 and waking at 8, they sleep at 8 and wake at 6

22
Q

when they attempt to adhere to a later bedtime what occurs?

A

they will continue to have an early wake time due to the shift in circadian rhythm

23
Q

how is ASPD perpetuated

A

a persons adverse exposure to light can maintain their undesired advance circadian rhythm. by going to bed early and then waking early, a person isn’t exposed to the regular evening low light and morning bright light signals maintain the disorder

24
Q

what are some symptoms and how can they increase in severity?

A

symptoms can get more severe when work or social demands require a schedule that doesn’t match the persons natural sleep-wake cycle

25
Q

how can bright light therapy be used as a treatment for ASPD?

A

exposed to the bright light source in the evening when feeling sleeping
acts as an external cue to the SCN and promotes wakefulness, causing a delayed melatonin release to occur at a more appropriate sleeping time
encourages the SCN to signal cortisol release later in the morning at a more appropriate time

26
Q

how can shift work cause a circadian rhythm sleep disorder?

A

when a person regularly works outside of normal business hours, particularly at night and the very early morning. This can include a consistent night shift or a rotating schedule, in round-the-clock professions such as health care, hospitality, factory work, transport and travel.

27
Q

what does shift work do to circadian rhythms

A

can put a person’s sleep wake schedule in direct opposition to the regular day-night environmental hours resulting in distress and dysfunction due to excessive sleepiness and impaired sleep at home afterwards

28
Q

what can shift work lead to in terms of cognitive effects

A

sleep disruption can lead to decreased judgement, poor decision making which then leads to behavioural effects like making more errors or accidents which then leads to affective effects like being unable to control ones temper or being easily irritated

29
Q

what biological impacts does shift work have

A

People who do shift work tend to disrupt their sleep-wake cycle as the body is not biologically
programmed to stay awake well into the late hours
of the night. This disruption in how a person is
exposed to light (working at night, sleeping in daytime) also disrupts the normal release of melatonin.

30
Q

what cues impact shift work?

A

Shift work disorders are caused by problems with external cues as a person needs to be awake when it’s dark outside and sleep when it’s light outside.

31
Q

how much of the population does shift work impact?

A

5-10% of the population- they work during nights particularly those middle aged-

32
Q

diagnosis of shift work

A

Diagnosis depends on how severe the symptoms are and the level of distress experienced by the person.

33
Q

what are some consequences of a circadian rhythm disorder caused by shift work

A

poor performance at work, interpersonal problems, increased risk of accidents, poor mental wellbeing

34
Q

prolonged shift work and physical health problems links

A

research has consistently found a link between prolonged shift work and physical health problems like gastrointestinal disorders, cardiovascular diseases, diabetes and cancer

35
Q

when do symptoms reduce for shift work?

A

when they can spend longer on one shift rotation before changing. Where rotating schedules are required, they should ideally shift forward, such as from morning shift, to afternoon shift, to evening shift, to allow a person the best chance to adjust. If a person working night shifts can commit to a more nocturnal routine for their social and other commitments, it may help their sleep–wake cycle become more consistent, and reduce symptoms. When a person returns to a typical, consistent daytime shift routine, then their symptoms can also resolve.

36
Q

how can BLT be used as treatment for shift work related sleep disorders

A

an individual is best to be exposed to the bright light source before beginning their shift at work to promote wakefulness and alertness
this promotes sleepiness at a later more suitable time, whether that be morning or afternoon

37
Q

What are circadian rhythm sleep disorders?

A

Circadian rhythm sleep disorders are a category of sleep disorders characterised by a persistent pattern of sleep disruption when the circadian rhythm and the sleep-wake schedule are misaligned.

38
Q

What is the difference between a Delayed Sleep Phase Syndrome and an Advanced Sleep Phase Disorder?

A

A Delayed Sleep Phase Syndrome causes a person to fall asleep later than desired, whereas an Advanced Sleep Phase Disorder causes a person to fall asleep earlier than desired.

39
Q

Describe shift work as a cause of circadian rhythm sleep disorder.

A

Shift work is a circadian rhythm sleep disorder characterised by working outside of the normal business hours, particularly at night and the very early morning, on a regular basis.

40
Q

Which sleep disorders can bright light therapy treat?

A

Bright light therapy can treat circadian rhythm sleep disorders.

41
Q

Explain how the hospital’s bedtime routine involving lights would have aided those with DSPS

A

The hospital consistently turns the lights off at 9 p.m., which would help induce the release of melatonin earlier in the night for patients, resulting in her feeling sleepy earlier. The hospital consistently turns the lights on at 6 a.m., which would help inhibit the release of melatonin in the early morning, resulting in patients feeling more awake.

42
Q

Mila has chosen to work a permanent night shift, beginning at 9 p.m. every night for the duration of the project. suggest a strategy for Mila’s mobile phone use that could help Mila achieve a better sleep during daylight hours.

A

Mila could ensure that she does not use her mobile phone before sleep or uses a night mode or other screen filter option, as well as ‘muting’ the volume so she is not disrupted during her sleep. She could also use the light from the phone in the evening while she is working to decrease melatonin release and promote wakefulness.