8.ANS IIII

Question 1

Describe Nicotinic Receptors.

Answer 1

-Ligand gated ion channels and are permeable to cations.

-Has a different isoform at muscles and ganglia.

-Has two different isoforms N1 or NM and N2 or NN

-NM are located at the neuromuscular junction.

-NN are located at the ganglia

-requires binding of two acetylcholine molecules

-Has 5 subunits

Question 2

Name the two agonists for Nicotinic receptors.

Answer 2

-Acetylcholine and nicotine.