(8.2) Visual Systems Flashcards
What is the retina?
The retina is the sensory organ of vision
What are the three main layers of a retina?
photoreceptor, intermediate layer and ganglion cell layer
What is the photoreceptor cell made up of?
Photoreceptor layers - Rods and cones (closest to the surface
What is the intermediate layer made up of?
Intermediate layer - Bipolar, horizontal, and amacrine cells
What is the ganglion cell made up of?
Ganglion cell layer - Retinal ganglion cells: midget & parasol
Rods and cones respond to…
light intensity
In darkness, rods & cones constantly release…
neurotransmitter (glutamate)
Light is absorbed by a…
pigment in rods and cones
change in shape of photopigment triggers a
G-protein cascade that reduces glutamate release
photoreceptors are inhibited (deactivated) by
light
Photo receptors respond to
darkness
When photo receptors respond to darkness they…
Pump out neurotransmitters creating action potentials
The intermediate layer Transforms light (brightness) information into
contrast information
What are the two types of bipolar cells?
ON and OFF
ON bipolar cells are inhibited or exhibited by input
inhibited
OFF bipolar cells are inhibited or excited by input
excited
What is a Parasol?
Large dendritic trees, Combine inputs from many bipolar cells
Small dendritic trees, Combine…
inputs from few bipolar cells
What is signal transduction?
Receptors translate light into neural signals for light intensity
Signals for light intensity are converted into
signals for contrast (differences in light intensity) by bipolar and ganglion cells
What are visual receptive fields?
the region of sensory space that evokes a response in a neuron
What are the characteristics of visual receptive fields?
- RFs have a position and a size
- RFs can have both excitatory and inhibitory sub regions
- Cells respond to light hitting certain areas
ON RFs respond to an increase or decrease in light intensity
increase
OFF RFs respond to an increase or decrease in light intensity
decrease
What are the characteristics of Retinal Ganglion Cell Receptive Fields?
- Most have ‘centre-surround organisation’
- Opposite response to light in centre and surround
Centre-Surround RFs are Formed by…
by Lateral Inhibition neighbouring neurons inhibit each other
The LGN consists of ____ layers
six
How do LGN layers differ?
- The kind of cells they contain
- What type of visual input they receive
- Which eye they receive input from
- Relay station
What are the Two Main Visual Pathways in the LGN?
Magnocellular (M) pathway and Parvocellular (P) pathway
What are the characteristics of the -Magnocellular (M) pathway?
- Inner two layers (1 & 2)
- Receive input from parasol ganglion cells
What are the characteristics of the Parvocellular (P) pathway
- Outer four layers (3,4,5,6)
- Receive input from midget ganglion cells
Receptive fields in LGN are similar to those of…
retinal ganglion cells (circular centre-surround)
What is the function of the LGN?
- Relay station between eye and brain
- Response properties similar to retinal ganglion cells
- But receives massive feedback from cortex
- 10x as many connections as from the eye!
- First site of attentional gating/enhancement
- Sleep-related gating of sensory input to cortex (reticular formation)
- Feedbacks info from the cortex
What is the V1 primary cortex?
- Also known as the striate cortex
- First site of visual processing in cortex
- Largest area in the brain
Most LGN neurons project to…
V1
V1 consists of how many layers?
six layers (like all of cortex) with several of the layers divided into sublayers
Layer 4 in the v1 consists of…
Layer 4 divided into 4A, 4B, 4C , 4C
Axons from LGN terminate…
(synapse with) cortical neurons in layer 4 (IV) of V1
Parvocellular (P) pathway projects to what layer in the V1…
-Project to layer 4C
The Parvocellular (P) pathway split into two new pathways…
- P-B pathway: colour (blobs)
- P-I pathway: orientation (interblobs)
What layer does the Magnocellular (M) pathway project to?
-Project to layer 4C and then onward to 4B
What are cells in 4B sensitive to?
- Cells in layer 4B are sensitive to movement
- Some are binocular and disparity/depth sensitive
Most cells in V1 are…
binocular (respond to stimulation in either eye)
Cells in layer 4 that receive input from LGN are…
monocular (respond only to one eye)
What is ocular dominance?
Most cells respond better to stimulation from one eye or the other
What is ocular dominance columns?
Cells preferring each eye are clustered into ~1mm thick slabs
What is the function of V1
-Topographic (retinotopic) organisation
-Contains a ‘map’ of the visual field
-Detailed maps of orientation, colour, spatial scale, motion direction, 3D depth
-Projects to most higher visual areas in cortex
-For each part of the visual scene, V1 computes:
orientation, spatial frequency, motion, colour, depth
-V1 cells respond best to limited range of
temporal frequency (flicker rate; how quickly stimuli change over time)
-Cells in the M pathway respond better to fast or slower flicker
fast
-Cells in the P pathway respond best to fast or slower flicker
slower
Neurons in V1 project to higher or lower visual cortical areas
Neurons in V1 project to higher visual cortical areas (extrastriate cortex): V2, V3, V3A, V4, V5…
Projections are…
Projections are topographic - each of these areas also contain a map of the visual field
What stimuli does V5 respond to?
V5 (MT): motion (M pathway)
What stimuli does V4 respond to?
V4: shape and colour (P pathway)
What stimuli does V3/3A respond to?
V3/V3A: motion boundaries and textures (M/P pathways)
What are the characteristics of the V2?
- Divided into multiple ‘stripes’:
- Thick stripes (M pathway): Sensitive to orientation and movement, Sensitive to disparity (depth)
- Thin stripes (P pathway): Sensitive to colour, Not orientation-selective
- Inter-stripes (P pathway): Orientation-selective, Not direction-selective
The P pathway projects to
V4
Damage to V4 causes…
- Damage to human V4 impairs colour perception
- But not clear if human V4 is same as in monkey!
- Also involved in shape discrimination
The M pathway projects to)
V3/V3A and V5 (MT
What are the characteristics of the Cells in V3/V3A
- Selective for orientation
- Respond to motion boundaries (dynamic form)
What are the charactertistics of the -Cells in V5 (MT)?
- Selective for motion direction and speed
- Process information on motion and stereoscopic depth