(2) Functional Neuroanatomy Flashcards
What is the neuron doctrine?
- Are the basic unit of the nervous system
- Are distinct and separate from each other (rather than a single network)
- Have cell bodies, axons and dendrites
- Transmit information – in one direction only
What does the neuron do?
Receives and processes signals: Collects information, integrates information, conducts information and outputs information
What happens when a neuron connects to another neuron?
- Can stimulate other neurons (excitatory synapses/neurons)
- Can inhibit other neurons (inhibitory synapses/neurons)
- Can receive input from many neurons
- Can send output to many neurons
What are Glial cells?
also known as glia or neuroglia. Nonneuronal brain cells that provide structural, nutritional and other types of support to the brain
-Neurons and Glia are the…
- Building blocks of the NS and small
- Low (or no) contrast under microscope
- Special chemical techniques
- Static staining and fibre tracing
What do neurons do?
Receive, process, transmit and output information
The brain consists of a myriad of interconnected …
neural circuits performing under different functions
The function of the neural circuit depends on:
How the neurons are connected, how strong the connections (synapses) are and whether the connections (synapses) are excitatory (EPSP) or inhibitory (IPSP)
The function of the neural circuit can change through changes in…
synaptic strength
What functions do glial cells have?
- Were thought to just hold things together
- Protective function
- Metabolic function
- More to come in next years
- Divide throughout life
What are the 4 types of glia?
- Astrocytes: star shaped
- Oligodendrocytes: few extensions
- CNS (central nervous system)
- (Microglia: smaller than rest)
What are Astrocytes?
- Attach to the blood vessels and neurons
- Provide physical support
- Separate synapses
- Clean up debris
What are Oligodendrocytes?
- Support axons
- Insulate axons & speed up information transmission
- Wrap around them: myelin sheath
- In PNS: Schwann cells
What is Multiple Sclerosis?
- Demyelinating disease
- Induces numerous scars (multiple scleroses) in the brain
- Immune system attacks the myelin produced by oligodendrocytes
- Probably an autoimmune disease
- Inflammation of CNS nerves
- Affects insulating layer of axons
What is Microglia?
- Aren’t really a glia
- Precursors of blood cells
- Part of the brain’s immune system
- Related to macrophages
- Eat up debris and hostile bits
What is the CNS?
brain and the spinal cord
What is the PNS?
All the nerves and neurons that reside outside or extend beyond the CNS
What is a Nerve?
an enclosed bundle of axons
What are the Structural subdivisions of the PNS?
cranial nerves and spinal nerves
What are the Functional subdivisions of the PNS?
somatic nervous system, autonomic nervous systems, sympathetic nervous system, parasympathetic nervous system
31 Pairs of Spinal Nerves
-One pair for each spinal segment: 8 cervical nerve pairs, 12 thoracic nerve pairs, 5 lumbar nerve pairs, 5 sacral nerve pairs and 1 coccygeal nerve pair
Each nerve has a
Ventral (toward front) root
What are efferent fibres?
projecting away from the CNS
What are afferent fibres?
projecting towards the CNS
What is the Somatic nervous system?
-Part of the PNS that controls voluntary body movements and conducts sensory information
Autonomic nervous system: Was thought to be independent and part of the PNS that controls…
homeostasis, in charge of circulation, breathing, digestion, sexual function
What is the brain and skull?
- The largest part of the nervous system
- Cushioned by fluid, protected by bone
What is the Brain protected by?
skull
What is the Spinal cord protected by?
vertebrae
What are Meninges?
the three protective sheets of tissue - dura mater, pia mater and arachnoid - that surround the brain and the spinal cord
The CNS floats in the
cerebrospinal fluid (CSF) -
What is the CSF for?
- Protection
- Nutrition
- Outside the CNS
- Sub-arachnoid space
- Inside the CNS
- Four ventricles
- Central canals
What is white matter?
a shiny layer underneath the cortex that consists largely of axons with white myelin sheaths
What is grey matter?
areas of the brain that are dominated by cell bodies and are devoid of myelin