Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Basic sciences > 8.1.2014 > Flashcards

8.1.2014 Flashcards

1
Q

side effects of IV acyclovir

A

nephrotoxicity

neurotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

acyclovir congener with long t1/2

A

valacyclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

dose limiting adverse effect of ganciclovir

A

myelosuppression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

dose limiting toxicity of cidofovir

A

nephrotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

cidofovir is active against

A

HSV
CMV
adeno virus
papilloma virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

advantage of foscarnet over other related anti virals

A

Does not need activation by host cell or viral kinases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

side effect of foscarnet

A

nephrotoxicity
hypocalcemia
hypomagnesemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

anti sense oligonucleotide active against CMV

A

fomivirsen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

amantidine and rimantidine are active only against

A

Influenza A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

neuraminidase inhibitor that can be given IV

A

peramivir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

route of admn of zanamavir

A

inhalational

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

drug of choice for chronic HBV

A

entecavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

adverse effect of ribavirin

A

dose dependant hemolytic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

new drugs for hepatitis C

A

sofosbuvir

simprevir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

beta tubulin polymerisation inhibitors

A

albendazole
mebendazole
thiabendazole
triclabendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

anti helminths causing spastic paralysis

A

pyrantel

levamisole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

anti helminths causing flaccid paralysis

A

piperazine

ivermectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

mech of action of praziquantel

A

influx of calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

drug of choice for all nematode infections

A

albendazole

20
Q

DOC for enterobius

A

mebendazole

21
Q

Ivermectin is drug of choice for

A

onchocerca

strongyloides

22
Q

DOC for dracunculiasis

A

metronidazole

23
Q

DOC for all trematode and cestode infections

A

praziquantal

24
Q

DOC for fasciola hepatica

A

triclabendazole

25
Q

DOC for hydatid disease

A

albendazole

26
Q

endogenous antiepileptic substance

A

adenosine

27
Q

antiepileptics acting by use dependant Na+ blockade

A 
phenytoin
carbamazepine
SVP
lamotrigene
topiramate
lacosamide
28
Q

MOA of ganaxolone

A

GABAnergic

29
Q

felbamate inhibits

A

NMDA receptors

30
Q

topiramate inhibits

A

kainate receptors

31
Q

characteristic adverse effect of trimethadone

A

hemarlopia(photophobia+glare effect)

32
Q

vigabatrin is DOC for

A

infantile spasms associated with tuberous sclerosis

33
Q

DOC for infantile spasms

A

ACTH

34
Q

adverse effects of vigabatrin

A

retinal atrophy

35
Q

anti epileptic indicated in depressive phase of bipolar disorder

A

lamotrigene

36
Q

adverse effect of lamotrigene

A

SJS/TEN

37
Q

DOC for diabetic and post herpetic neuralgia

A

GABApentin

38
Q

anti epileptics that can cause renal stones

A

zonisamide

topiramate

39
Q

antiepileptic that can cause weight loss

A

topiramate

40
Q

adverse effect of felbamate

A

hepatotoxicity

aplastic anemia

41
Q

anti epileptic that is an AMPA receptor inhibitor

A

perampanel

42
Q

newly approved drug for lennox gestaut

A

rufinamide

43
Q

drugs for absence seizures

A 
SVP
ethosuximide
lamotrigene
trimethadone
ganoxolone
44
Q

CCB causing hyperprolactinemia

A

verapamil

45
Q

sulfasalazine is a combination of

A

5-ASA and sulfapyridine

46
Q

adverse effects of sulfapyridine

A

nausea,vomiting
bone marrow suppression
oligospermia

Basic sciences (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions