1.1.2014 Flashcards

1
Q

adverse effects of rapid admn of fosphenytoin

A

arrythmia
CVS collapse
coma

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2
Q

fetal hydantoin syndrome

A

cleft lip
cleft palate
congenital heart disease

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3
Q

adverse effects of phenytoin

A
gum hypertrophy
hirsuitism
coarsening of facial features
megaloblastic anemia
VitD deficiency
VitK deficiency
hyperglycemia
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4
Q

QUININE IS gametocidal agnst

A

vivax and ovale

not against falciparum

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5
Q

5’ de iodinase is found in

A

liver
kidney
brain
pitutary

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6
Q

only indication for T3

A

myxedema coma

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7
Q

drugs inhibiting iodine uptake

A

thiocyanate

perchlorate

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8
Q

drugs inhibiting thyroid hormone secretion

A

NaI
KI
Li

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9
Q

Drugs inhibiting peripheral conversion

A

PTU
propranolol
amiodarone

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10
Q

time to effect of antithyroid action of PTU,methimazole,carbimazole

A

1-3 wks

till stores are used up

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11
Q

most common adverse effects of antithyroid drugs

A

maculopapular rash

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12
Q

most serious adverse effect of antithyroid drugs

A

reversible agranulocytosis

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13
Q

fastest acting antithyroid drugs

A

iodides

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14
Q

contraindications for I131

A

age<35 yrs
pregnancy
co existing ophthalmopathy

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15
Q

graves ophthalmopathy is aggravated by

A

thiazelidenidiones

I131

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