8. Acid/Base Chem Flashcards
what is an acid vs a base
acid - donates H+
base - accepts H+
H+ (free protons) are immediately hydrated into _____
hydronium ions (H3O+)
differences between a strong vs weak acid
strong acid/ base = complete proton dissociation
weak acid/ base = incomplete proton dissociation
conjugate acid vs base
conj acid = donates a proton (HA)
conj base = accepts proton (A-)
low pKa =
stronger acid
pKa
50% protonated and 50% deprotonated
what is mid point of a titration
when pKa = pH
polyprotic acid
compound that may lose more than 1 proton
the pH of biological systems is maintained by ______
buffers
what is the physiological pH range
7.35 to 7.45
what are buffers made of and what is the buffering range
weak acid and conj base
or
weak base and conj acid
buffering range = pKa +/- 1
at midpoint of titration it is the ____ ____ capacity
maximum buffering capacity
what are universal buffers
buffers which have overlapping buffering regions
what is major buffer system of blood
carbonic acid-bicarbonate (H2CO3/HCO3-)