8-22 SLEEP Flashcards

1
Q

Sleep is the ____state between _____and _____

A

Sleep is the INTERMITTENT state between WAKEFULNESS and DEATH

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2
Q

List and describe the 3 states of Being

A
  1. Wake
  2. NREM sleep=Active body/physical restoration/Stages N1, N2, N3
  3. REM sleep=Active Brain/Mental Restoration
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3
Q

1) All species have _____ sleep in EARLY LIFE that will ___[INC/DEC] with age
2) All mammals have _____sleep

A

1) All SpeCies have REM Sleep in early life but this DEC as general species age
2) All MAMMALS have NREM/REM Sleep

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4
Q

Sleep depends on ____, _____, ______ and _______

A

Human Sleep depends on AGE, DRUGS/DISORDERS, COURSE OF WAKE/SLEEP CYCLE AND COURSE OF NREM/REM

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5
Q

What is the NREM:REM sleep ratio FOR INFANTS?

A

Infants NREM:REM= 50%NREM: 50%REM

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6
Q

What is the NREM:REM sleep ratio FOR ADULTSSS?

A

ADULTS NREM:REM= 75-80%NREM : 20-25%REM

“WE SPEND MORE TIME IN PHYSICAL/BODY RESTORATION DURING SLEEP!”

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7
Q

NREM sleep occurs mostly in the ___half of sleep and is linked to ________

A

NREM sleep occurs mostly in the FIRST half of sleep and is linked to PRIOR LEVEL OF WAKEFULLNESS

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8
Q

REM sleep occurs mostly in the ____half of sleep and is linked ______

A

REM sleep occurs mostly in the SECOND half of sleep and is linked to CIRCADIAN RHYTHM

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9
Q

What happens to a Childs sleeping patterns as it grows up?

A

Children sleeping[wake/sleep pattern] gradually becomes RESTRICTED TO THE NIGHT as they get older

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10
Q

Describe Normal Sleep in Children [2]

A
  • No Sleep Onset REM Periods (SOREMs) until 3 mo. old

* NREM stages 3-6 months

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11
Q

Describe Normal Sleep in ADULTS [2]

A

1) Adult sleep is entered through NREM stage first

2) REM cycles every 90-120 minutes

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12
Q

Circadian Rhythm

2)Physiologically where does this come from?

A

Intrinsically NATURAL RHYTHMS of sleep even w/out environmental cues like the sun. Not exactly but approximately a 24 hour rhythm
2)Comes from the circadian pacemaker in the hypothalamus’ suprachiasmatic nuclei(biological clock)

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13
Q

Entrainment [2]

A

Stimuli (Zeitgebers) signal the time of day and can shift circadian clocks systemically–> enables Circadian Rhythms to synchronize w/ the environment.
2)Can be either photic or non-photi

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14
Q

In the two-process model of sleep Process S=______ and Process C = ______

A

Process S= homeoStatic INC in sleep pressure w/INC time awake
**Process C=Circadian nadir occurring early in the morning

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15
Q

What is the Sleep debt “payback” ratio?

A

For ever 2.5 hours you miss in sleep(debt) you will have to payback 1 hour to make up for it! 2.5:1 ratio

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16
Q

What are some Known effects of Sleep Deprivation

A
  • INC car crashes
  • Major industrial accidents (cheronobyl, 3 mile island)
  • INC risk of blood-borne pathogen exposure accidents in EM residents (sticking self with needle)
17
Q

Describe the Epworth Sleepiness Scale

A

0=no chance of dozing off
1= Slight chance of dozing off
2= Moderate chance of dozing
3=HIGH chance of dozing off

18
Q

What are the 4 Diagnostic Test used for sleep?

A
  1. PSG!/Polysomnography :Scoring & Staging(EEG, EMG, Airflow, Respiratory Effect, EKG)(3 stages Wake vs. NREM vs. REM)
  2. Multiple Sleep Latency Test [MSLT]
  3. Maintenance of Wakefulness Test
  4. Actigraphy
19
Q

Describe the Multiple Sleep Latency Test

A

Used to Diagnose sleep disorder=preceded by an all-night in lab PSG the well-cntrolled MSLT uses (5) 20-min naps to test tendency of falling asleep during usual wake hours (i.e. Narcolepsy)

20
Q

What are the Parameters measured in MSLT?

A

MSLT (multiple sleep latency test) measures

  1. average latency[eyes close but not sleep] to sleep onset
  2. Appearance of REM sleep
21
Q

What are the NORMS for sleep latency: [4]

A

latency: Lying in bed w/eyes closed but not yet sleep
* 0-5 min of latency=severe hypersomnia=narcoleptic=pt goes to sleep VERY FAST

  • 5-10 min of latency=borderline narcoleptic
  • 10-20 min latency=NORMAL :-)

*2 or more naps with REM periods=Abnormal

22
Q

Describe the “Maintenance of Wakefulness Test”

A

Will test pt ability to STAY AWAKE–> by requiring them to sit up in dimly lit room and stay awake for 40 minutes. Repeats this 4 times throughout the day.

23
Q

Describe Actigraphy

A

Minimally invasive cheap at-home method, worn as a watch and used to capture all types of sleep score information that can be interpreted later!

24
Q

1) Psychological Insomnia

2) Treatment?

A

PI=Present for at least 1 month and described as heightened arousal in bed and/or evidenced sleep difficulty
2)TRMNT: Cognitive Stimulus control, Sleep restriction, Rx

25
1) Obstructive Sleep Apnea! [6] 2) How do you diagnose this? 3) What is treatment for OSA?
1)Obstctive= narrowing/occlusion of upper airway during sleep-->Loud snoring, morning sore throat/HA, Elevated BMI, crowded oropharynx and HTN 2) Dx with PSG/POLYSOMNOGRAPHY 3) TRMNT OSAS: Oral Appliance mouthpiece (moderate severity) or CPAP (SEVERE OSA) while sleep
26
1)Restless Legs Syndrome
1)Pt has Restless Legs if they have the U-R-G-E!! U=unpleasant limb sensations w/urge to Move R=Rest helps alleviate Sx G=getting up/mvmnt helps alleviate Sx E=Evening or Night exacerbates Sx
27
1) Narcolepsy 2) When does this typically onset? 3) What is Secondary Narcolepsy? 4) What are the MSLT findings for Narcolepsy? [2]
1) Sleepiness and sx caused by abnormal regulation of REM/2nd half sleep 2) Narcolepsy onsets during adolescence usually 3) Sec Narc= Head trauma (stroke, MS, CNS infection) causes sx similar to regular Narcolepsy 4)MSLT=Sleep latency is 0-5 min AND pt has 2 or more REM periods in 5 out of 20 naps
28
Parasomnias
- Disorders that disrupt sleep but don't originate from problems w/the wake-and-sleep state itself. - Are PHYSICAL EVENTS OR EXPERIENCES(movements, dreams, behaviors, perceptions) that INTERRUPTS sleep
29
Sleepwalking!
Complex Automatic motor activity during deep sleep associated w/amnesia of the event!
30
1) Sleep Terrors :-( | 2) What is this also known as...?
1) MOST COMMON IN MALE KIDS-involves sudden extreme autonomic arousal from deep sleep w/terror &confusion on wake 2) Sleep Terrors are AKA "Pavor nocturnus"
31
REM Sleep Behavior Disorders are characterized by what...
Dream enactment behavior w/loss of muscle control in REM 1-Verbalizations/Singing 2-Violent/agitated bed behavior {hitting partner} 3-Walking/running
32
Sleep-Related Eating Disorder [4]
Prepares food and sometimes non-edible objects to eat w/amnesia of the event 2) subcategory of sleep walking 3) MORE COMMON IN WOMEN 4) Arises from NREM(SWS) sleep