7. Renal Replacement Therapy and Dialysis Flashcards

1
Q

What 7 things can the kidneys do?

A
Salt Removal
Water Removal
Electrolyte Balance
Acid-Base Balance
Toxin Removal
Make erythropoietin
1-A Hydroxylate Vitamin D
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2
Q

What does Dialysis do?

A
Salt Removal
Water Removal
Electrolyte Balance
Acid-Base Balance
Toxin Removal
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3
Q

What is Haemodialysis?

A

When blood is filtered across a membrane using a machine

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4
Q

How often is Haemodialysis done?

A

Minimum of 4 hours, 3 times a week

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5
Q

What are the Principles of Haemodialysis?

A
  1. Blood is exposed to a Fluid Dialysate across a Biocompatible Membrane
  2. Small molecules can pass through, Large cannot
  3. Concentration gradient allows Diffusion across the membrane
    - Removes waste
    - Replaces ions/molecules
  4. Water is DRIVEN through the membrane via Ultrafiltration
  5. UF clears solutes via Convection
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6
Q

What do you require during Haemodialysis for it to work

A

Anticoagulation (Stops clotting)

Vascular Access (Means of taking blood)

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7
Q

Name three ways of Vascular access for a Haemodialysis machine

A
  1. AV fistula
  2. AV graft
  3. Tunnelled Catheter
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8
Q

What are the two main dialysis complications?

A
  1. Access complications

2. Dialysis complications

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9
Q

Name 6 Access complications of Haemodialysis

A
  1. Distal Ischaemia (AVF/G)
  2. Aneurysm (AVF/G)
  3. Failure of Access
  4. Thrombosis
  5. Central Venous Stenosis (Tunnelled Catheter)
  6. Infection
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10
Q

Name 3 Dialysis complications of Haemodialysis

A
  1. Hypotension
  2. Reactions to dialysis (Headache/Cramp)
  3. Inadequate Dialysis dose
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11
Q

What is Peritoneal Dialysis?

A

Dialysis done at home by patient/care/HCW

Focusing on Patient Autonomy and Self-care

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12
Q

How does PD work?

A
  1. Semi-permeable peritoneal membrane lines the abdominal cavity
  2. Membrane allows diffusion of toxins/electrolytes into the dialysis solution
  3. UF occurs via osmosis (removes fluid)
  4. Steady state of toxin clearance and fluid management is achieved due to daily performance of dialysis
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13
Q

What are the Three Main Types of Dialysis?

A
Haemodialysis
- Home/In-centre
Peritoneal Dialysis
- Home/CAPD and APD
Continuous Veno-Venous Haemofiltration
- Inpatient treatment in Critical care setting
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14
Q

What does CAPD stand for in Haemodialysis?

A

Continuous Ambulatory Peritoneal Dialysis

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15
Q

How does CAPD work in Haemodialysis?

A
  1. GIve 4-5 Exchanges a day
  2. Fluid starts in Peritoneal Cavity
  3. DRAIN: Fluid is drained by gravity in a closed system
  4. FLUSH: Small amount is flushed into a drain bag to clear the line
  5. FILL: New fluid runs into peritoneal cavity via closed system
  6. DWELL: Fluid dwells for 4-6 hours
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16
Q

What does APD stand for in Haemodialysis?

A

Automated Peritoneal Dialysis

17
Q

How does APD work in Haemodialysis?

A
  1. Patient has a cycler machine
  2. Dialysis takes place over night for ~8 hours
  3. Usually better for people who work
18
Q

What are the main complications of PD?

A
  1. Membrane Failure
  2. Inadequate dialysis
  3. Catheter dysfunction/malposition
  4. Encapsulating Peritoneal Sclerosis
  5. Pain
  6. Infection (Peritonitis)
  7. Peritoneal Leak
19
Q

Why do some people choose to not have dialysis?

A
  1. Heart Disease
  2. Terminal diagnosis with short prognosis
  3. Frailty
  4. QoL
  5. Patient Choice
20
Q

What is the alternative management of kidney issues?

A

Manage symptoms with medication via multi-disciplinary approach

  • Doctors
  • Nurses
  • Dieticians
21
Q

How do we decide what treatment to use for a patient that may/may not need Dialysis?

A
  1. Patient + Clinician shared care decision-making
  2. Lifestyle
  3. Personal choice
  4. Technical
  5. Patient Factors
    - Technical (PD not possible after major abdominal surgery)
    - Comorbidities (Heart failure/Instability)
    - Frailty