7: Mechanisms of antibiotic resistance

Question 1

Bacteria are rapidly developing ___ to antibiotics.

Answer 1

resistance

Question 2

What complex communities of microbes are resistant to antimicrobial agents?

Answer 2

Biofilms

Question 3

In biofilms, ___ cells aim to tolerate antimicrobial agents so they can restart the population.

Answer 3

persistor

Question 4

What genetic change increases the chance of a population developing resistance to an antimicrobial therapy?

Answer 4

Mutation

Question 5

What about bacteria make them more likely to develop mutations?

Answer 5

Rapid growth and multiplication time

Question 6

Evolution of resistance occurs most quickly when the selection pressure (e.g use of penicillin) is ___.

Answer 6

high

Question 7

How many a bacterium acquire resistance to an antibiotic?

Answer 7

Horizontal gene transfer

Question 8

Which enzyme, produced by resistant bacteria, breaks down penicillin?

Answer 8

ß-lactamase

Question 9

not easily turned into flashcards