7. Diabetes Technology23 Flashcards
What can CGM be used for in managing hospitalized individuals?
CGM can be used in conjunction with BGM to manage hospitalized individuals.
According to the article, what is the approved method for glucose monitoring in hospitals?
Point-of-care BGM
Who should be supported to continue using diabetes devices in an inpatient setting or during outpatient procedures?
People with diabetes who are competent to safely use diabetes devices such as insulin pumps and continuous glucose monitoring systems.
What should be established before people with diabetes can continue using diabetes devices in an inpatient setting or during outpatient procedures?
Competency and proper supervision.
What is the purpose of a ‘do-it-yourself’ (DIY) system in diabetes technology?
The purpose of a ‘do-it-yourself’ (DIY) system is to combine an insulin pump and a rtCGM with a controller and an algorithm designed to automate insulin delivery.
NOT FDA APPROVED
What should health care professionals do in regards to systems not approved by the U.S. Food and Drug Administration?
Health care professionals should assist in diabetes management to ensure the safety of people with diabetes.
What are some examples of systems individuals with diabetes may be using that are not approved by the U.S. Food and Drug Administration?
Some examples include do-it-yourself closed-loop systems and others.
What are some alternative pump options for people with type 2 diabetes?
Disposable patch-like devices that provide continuous subcutaneous infusion of rapid-acting insulin with bolus insulin in 2-unit increments or bolus insulin only delivered in 2-unit increments used in conjunction with basal insulin injections.
Do individuals with type 2 diabetes consistently experience reductions in A1C levels when USE PUMP compared with MDI?
No, reductions in A1C levels are not consistently seen in individuals with type 2 diabetes when compared with MDI.
What benefits may diabetes technology have in relation to exercise-related hypoglycemia?
Diabetes technology may lower the risk of exercise-related hypoglycemia.
How can AID systems potentially impact A1C levels?
AID systems may reduce A1C levels.
What is required for currently used hybrid closed-loop systems to calculate prandial doses?
The manual entry of carbohydrates consumed is required.
What adjustments must be announced for currently used hybrid closed-loop systems?
Adjustments for physical activity must be announced.
What do all AID systems on the market today do?
All AID systems on the market today adjust basal delivery in real time and some deliver correction doses automatically.
What are the three components of Automated Insulin Delivery Systems
AID?
The three components are an insulin pump, a continuous glucose monitoring system, and an algorithm for insulin delivery calculation.
What do AID systems do to mimic physiologic insulin delivery?
AID systems increase and decrease insulin delivery based on sensor-derived glucose levels.
What did the (ASPIRE) trial show about sensor-augmented insulin pump therapy with a low glucose suspend function?
The (ASPIRE) trial showed that sensor-augmented insulin pump therapy with a low glucose suspend function significantly reduced nocturnal hypoglycemia over 3 months without increasing A1C levels.
What type of pumps have been approved by the FDA?
Sensor-augmented pumps that suspend insulin when glucose is low or are predicted to go low within the next 30 min.
What is the purpose of the FDA approval for sensor-augmented pumps?
To allow pumps to suspend insulin when glucose is low or are predicted to go low within the next 30 min.
What is the preferred mode of insulin delivery for children under 7 years of age?
According to the content, pump therapy may be the preferred mode of insulin delivery for children under 7 years of age.
According to the article, what diabetes complications may insulin pump therapy help reduce in youth?
Insulin pump therapy may help reduce retinopathy and peripheral neuropathy in youth with diabetes.
may reduce the risk of diabetic ketoacidosis (DKA) and diabetes complications in youth.
What is the potential benefit of insulin pump therapy mentioned in the article?
Insulin pump therapy
What is the potential benefit of using insulin pumps?
Insulin pumps may reduce the rates of severe hypoglycemia compared with MDI.
What was a major adverse effect of intensified insulin therapy in the Diabetes Control and Complications DCCT Trial?
Hypoglycemia.
What does the abbreviation RCTs stand for in the given content?
RCTs stands for Randomized Controlled Trials.
According to the article, what improvement is observed in participants on insulin pump therapy compared to MDI with rapid-acting insulin analogs?
A modest improvement in A1C is observed.
What factor may contribute to better glycemic outcomes for participants on insulin pump therapy?
Higher socioeconomic status
What are some skin issues associated with pump usage?
Some skin issues associated with pump usage are lipohypertrophy and lipoatrophy.
Do measurement of C-peptide levels or antibodies predict success with insulin pump therapy?
There are no data to suggest that measurement of C-peptide levels or antibodies predicts success with insulin pump therapy.
When can pump therapy be started?
Pump therapy can be successfully started at the time of diagnosis.
What is the purpose of the PANTHER Program?
The PANTHER Program is designed to assist health care professionals and people with diabetes in choosing diabetes devices based on their individual needs and the features of the devices.
What resources can the PANTHER Program and pantherprogram.org provide?
The PANTHER Program and pantherprogram.org provide helpful websites to assist health care professionals and people with diabetes in choosing diabetes devices.
What did a systematic review and meta-analysis conclude about pump therapy?
Pump therapy has modest advantages for lowering A1C (-0.30% [95% CI -0.58 to -0.02]) and for reducing severe hypoglycemia rates in children and adults.
What are the advantages of pump therapy according to the systematic review and meta-analysis?
Pump therapy has modest advantages for lowering A1C (-0.30% [95% CI -0.58 to -0.02]) and for reducing severe hypoglycemia rates in children and adults.
What should individuals with diabetes who have been using continuous subcutaneous insulin infusion have?
Individuals with diabetes who have been using continuous subcutaneous insulin infusion should have continued access across third-party payers.
What population can insulin pump therapy be offered to for diabetes management?
Insulin pump therapy can be offered to youth and adults on multiple daily injections with type 2 diabetes who are capable of using the device safely (either by themselves or with a caregiver).
What factors should be considered when choosing an insulin pump device?
The choice of device should be made based on the individual’s circumstances, preferences, and needs.
Who should make the decision on which insulin pump device to choose?
The individual should make the decision based on their circumstances, preferences, and needs.
Who should be offered insulin pump therapy alone or with sensor-augmented pump low glucose suspend feature and/or automated insulin delivery systems for diabetes management?
Youth and adults on multiple daily injections with type 1 diabetes A or other types of insulin-deficient diabetes E who are capable of using the device safely (either by themselves or with a caregiver) and are not able to use or do not choose an automated insulin delivery system.
How should the choice of device be made for insulin pump therapy for diabetes management?
The choice of device should be made based on the individual’s circumstances, preferences, and needs.
What are the criteria for offering insulin pump therapy alone or with sensor-augmented pump low glucose suspend feature and/or automated insulin delivery systems for diabetes management?
The criteria include being on multiple daily injections with type 1 diabetes A or other types of insulin-deficient diabetes E, being capable of using the device safely (either by themselves or with a caregiver), and not being able to use or choosing not to use an automated insulin delivery system.
Who should be offered automated insulin delivery systems for diabetes management?
Youth and adults with type 1 diabetes A and other types of insulin-deficient diabetes E who are capable of using the device safely.
What factors should be considered when choosing an automated insulin delivery device?
The individual’s circumstances, preferences, and needs.
Which group of people should consider using automated insulin delivery systems?
Youth and adults with type 1 diabetes A and other types of insulin-deficient diabetes E who are capable of using the device safely.
What is the potential benefit of using shorter needles during injections?
Shorter needles (4–5 mm) may lower the risk of intramuscular injection and possibly the development of lipohypertrophy.
What is the unit increment of U-500 pens?
The unit increment of U-500 pens is 5 units.
In what settings are syringes generally reused?
Syringes are generally reused in resource-limited settings.
What do trials with insulin pens generally show in terms of glycemic outcomes?
Trials with insulin pens generally show equivalence or small improvements in glycemic outcomes compared with using a vial and syringe.
What is the effect of ingesting ascorbic acid (HYDROXYUREA in high doses?
Hydroxyurea Dexcom G6, Medtronic Guardian HIGHER SWNSOR READING
What is the effect of ingesting ascorbic acid (vitamin C) in high doses?
Ingesting ascorbic acid (vitamin C) in high doses can result in higher sensor readings than the actual glucose levels.
Which diabetes technology is known to have higher sensor readings than actual glucose levels when hydroxyurea is used?
Dexcom G6 and Medtronic Guardian are known to have higher sensor readings than actual glucose levels when hydroxyurea is used.
What is the biomarker used by the Tetracycline Senseonics Eversense Sensor?
The Tetracycline Senseonics Eversense Sensor uses bias within therapeutic concentration ranges.
What are two diabetes technologies mentioned in the article?
The two diabetes technologies mentioned in the article are Hydroxyurea Dexcom G6 and Medtronic Guardian.
Which medication can cause higher sensor readings than actual glucose in the Dexcom G6 system?
Acetaminophen