6. Glycemic Targets23 Flashcards
What can improve A1C with minimal hypoglycemia in people with type 2 diabetes?
Other strategies to assist them with insulin dosing.
How does real-time CGM help in managing hypoglycemia in people with impaired awareness?
Real-time CGM appears to be a useful tool for decreasing time spent in a hypoglycemic range in people with impaired awareness.
According to a recent meta-analysis, what impact did it reflect on hypoglycemic events in type 2 diabetes?
The recent meta-analysis did not reflect a significant impact on hypoglycemic events in type 2 diabetes.
Has any study reported a decrease in level 3 hypoglycemia? WITH CGM?
No, no study to date has reported a decrease in level 3 hypoglycemia.
According to the article, CGM showed a significant reduction in time spent?
Between 54 and 70 mg/dL
What is the range of improvement in A1C levels observed with CGM in people with type 1 and type 2 diabetes?
CGM improved A1C levels between 0.3 and 0.6%.
What is hypoglycemia unawareness also known as?
Hypoglycemia unawareness is also known as hypoglycemia-associated autonomic failure.
What are MICHANISM for hypoglycemia-associated autonomic failure?
1-Deficient counterregulatory hormone release.
2-diminished autonomic response are two risk factors for hypoglycemia-associated autonomic failure.
What are the different forms of glucagon available for injection?
The different forms of glucagon available for injection are traditional glucagon injection powder, intranasal glucagon, and ready-to-inject glucagon preparations for subcutaneous injection.
What factors should be considered when using glucagon products?
When using glucagon products, factors such as safety, efficacy, ease of use, and ensuring the products are not expired should be considered.
According to the provided content, what are CGM tools used for?
CGM tools are used to assess therapy and detect incipient hypoglycemia.
When is the use of glucagon indicated?
The use of glucagon is indicated for the treatment of hypoglycemia in people unable or unwilling to consume carbohydrates by mouth.
What is the purpose of using glucagon?
The purpose of using glucagon is to treat hypoglycemia in individuals who are unable or unwilling to consume carbohydrates by mouth.
What should an individual do after experiencing recurrent hypoglycemia?
The individual should be counseled to eat a meal or snack to prevent recurrent hypoglycemia.
What may lead to recurrent hypoglycemia unless more food is ingested after recovery?
Ongoing insulin activity or insulin secretagogues.
According to the article, what can increase insulin response without increasing plasma glucose concentrations?
Ingested protein FOR HYPOGLYCEMIA TTT
What should not be used to treat or prevent hypoglycemia, according to the article?
Carbohydrate sources high in protein
What is the potential treatment option for people with type 1 diabetes who have level 3 hypoglycemia and hypoglycemia unawareness that persists despite medical treatment?
Human islet transplantation may be an option, but it remains experimental.
What is the suggested treatment for people with type 1 diabetes who have hypoglycemia unawareness despite medical treatment?
Human islet transplantation, although experimental, may be considered as an option.
What is the proven effectiveness of CGM with automated low glucose suspend and hybrid closed-loop systems?
Reducing hypoglycemia in type 1 diabetes
What interventions may improve PEDIATRIC patient outcomes in HYPOGLYCEMIA?
Individualized glucose targets, patient education, nutrition intervention, physical activity management, medication adjustment, glucose monitoring, and routine clinical surveillance may improve patient outcomes.
What trial found an association of level 3 hypoglycemia with mortality?
The ADVANCE trial found an association of level 3 hypoglycemia with mortality.
What was significantly associated with subsequent episodes of level 3 hypoglycemia in the ACCORD trial?
Cognitive impairment at baseline or decline in cognitive function during the trial.
In the ACCORD trial, what level of hypoglycemia was significantly associated with cognitive impairment at baseline or decline in cognitive function?
Level 3 hypoglycemia.