7. Blood Donor Testing Flashcards

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1
Q

PLTs are stored at ___ for up to __ days

A

RT; 7 days

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2
Q

HTLV confirmatory test?

A

HTLV Western blot

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3
Q

a common community acquired infection that lies dormant in white blood cells and is harmless for most of the population

A

Cytomegalovirus (CMV)

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4
Q

Phenotyping for these for 6 are routinely performed on a subset of repeat donor sample

A

C/c E/e Kell Duffy Kidd S/s

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5
Q

3 things that happen during a lookback investigation?

A
  • Donor deferred; their previous donations are investigated
  • Hospitals that received blood are notified and asked to ID recipients
  • Recipients are tested
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6
Q

Environment where syphilis can’t survive

A

72 hrs in citrated blood at 1-6 degC

72 hrs at RT

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7
Q

The process of identifying and contacting recipients of blood components from a donor who, on a subsequent donation or testing, is confirmed to have tested positive for the presence of an infectious agent

A

LOOK BACK

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8
Q

This is the process of investigating a report of transfusion-associated infection in blood recipients who have already received blood components.

A

TRACEBACK

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9
Q

The only component capable of transmitting syphilis infection

A

Platelets

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10
Q

Purpose of TRACEBACK investigation?

A

Determine if any donor who provided blood for that recipient has tested positive for an infectious agent

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11
Q

_____ has been associated with adult T-cell leukemia

and myelopathy / tropical spastic paraparesis (HAM/TSP)

A

HTLV-I

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12
Q

Why is the risk of CMV infection related to blood products low in Canada

A

CMV = cell-associated virus and cellular components get LEUKOREDUCED in Canada

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13
Q

How often can plateletpheresis be done?

A

Every 2 weeks (14 days)

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14
Q

Minimum weight requirement to donate?

A

50kg/110lbs

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15
Q

Disease caused by Treponema pallidum

A

Syphilis

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16
Q

How does MHA-TP work

A

Sheep RBC coated w/ T. pallidum antigen => test for agglutination w/ patient plasma

17
Q

How often can plasmapheresis be done?

A

Every week (7 days)

18
Q

When would chagas be tested?

A

Donor is “at-risk” as indicated by questionnaire

19
Q

Why are platelets the only component capable of transmitting syphilis?

A

Storage of PLTs is at RT (cannot survive cold)

20
Q

Minimum Hgb requirements for male and female

A

Female 125 g/L

Male 130 g/L

21
Q

Assay used to detect antibody to T. cruzi

A

Chemiluminescent

22
Q

________ transfusions require CMV negative products

A

Intrauterine

23
Q

How often can male donors donate whole blood? Female?

A

Male - 56 days

Females - 84 days

24
Q

Test for Treponema pallidum

A

MHA-TP micro hemagglutination test

25
Q

How are platelet units tested for bacterial contamination?

A

Automated blood culture system

26
Q

Organism that causes chagas

A

Trypanosoma cruzi