7: acid base reg Flashcards
which enzyme systems and body functions are altered by [H+]
all
[H+] in the body is kept very ___ compared to other ions
low
___ blood pH is 7.4, while venous blood and interstitial fluid pH is 7.35
arterial
____ fluid pH ranges from 6.0-7.4 while ___ ranges from 4.5-8.0
-gastric HCl is 0.8
intracellular
urine
if arterial blood is below 7.4, a person is considered to have ___. but if the pH increases above 7.4, they have ___.
acidosis
alkalosis
the kidneys regulate __ [H+] by three mechanisms
- secretion of H+
- reabsorp of filtered HCO3-
- prod of new HCO3-
extracellular
2 main buffers in control of acid-base balance
phosphate
ammonia
in ___, tubular secretion of H+ is DECREASED
-H+ is to low for complete HCO3 reabsorp
alkalosis
in ___ tubular secretion of H+ is INCREASED
-increased reabsorp of HCO3
acidosis
if acidosis occurs because and increase in Pco2, it is considered __ acidosis
respiratory
if acidosis occurs bc of a fall in HCO3 it is considered ___ acidosis
metabolic
excess H+ in the renal tubules causes complete reabsorption of ___
HCO3
excess HCO3 cannot be reabsorbed bc of the lower levels of ___ secreted into the tubules, in renal correction of alkalosis
H+
only __% of amino acids available in the body are convertible
60
detection of low ___ levels in cells and in the blood plasma stim gluconeogenesis
carbohydrate